Layer-by-layer assembly of viral capsid for cell adhesion.

SuZ; NiuZ; LiS; LeeLA; WangQ

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Layer-by-layer assembly of viral capsid for cell adhesion.

机译：病毒衣壳的逐层组装，用于细胞粘附。

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Cowpea mosaic virus (CPMV)-based thin films are biologically active for cell culture. Using layer-by-layer assembly of CPMV and poly(diallyldimethylammonium chloride), quantitatively scalable biomolecular surfaces were constructed, which were well characterized using quartz crystal microbalance, UV-vis and atomic force microscopy. The surface coverage of CPMV nanoparticles depended on the adsorption time and pH of the virus solution, with a greater amount of CPMV adsorption occurring near its isoelectric point. It was found that the adhesion and proliferation of NIH-3T3 fibroblasts can be controlled by the coverage of viral particles using this multilayer technique.

机译：基于Cow豆花叶病毒（CPMV）的薄膜对细胞培养具有生物活性。使用CPMV和聚（二烯丙基二甲基氯化铵）的逐层组装，构建了定量可扩展的生物分子表面，并使用石英晶体微量天平，UV-vis和原子力显微镜对它们进行了很好的表征。 CPMV纳米颗粒的表面覆盖率取决于病毒溶液的吸附时间和pH值，其中CPMV的等电点附近吸附量更大。发现使用这种多层技术可以通过覆盖病毒颗粒来控制NIH-3T3成纤维细胞的粘附和增殖。

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来源
《Acta biomaterialia》 |2008年第4期|共6页
作者
SuZ; NiuZ; LiS; LeeLA; WangQ;
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原文格式 PDF
正文语种 eng
中图分类生物医学工程;
关键词
Viral; Layer;

机译：病毒层;

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专利

1. Layer-by-layer assembly of viral capsid for cell adhesion. [J] . SuZ, NiuZ, LiS, Acta biomaterialia . 2008,第4期

机译：病毒衣壳的逐层组装，用于细胞粘附。
2. Viral capsid assembly as a model for protein aggregation diseases: Active processes catalyzed by cellular assembly machines comprising novel drug targets [J] . Marreiros Rita, Mueller-Schiffmann Andreas, Bader Verian, Virus Research: An International Journal of Molecular and Cellular Virology . 2015,第Null期

机译：病毒衣壳装配作为蛋白质聚集疾病的模型：包含新型药物靶标的细胞装配机催化的活跃过程
3. Proteolytic Disassembly of Viral Outer Capsid Proteins Is Crucial for Reovirus-Mediated Type-I Interferon Induction in Both Reovirus-Susceptible and Reovirus-Refractory Tumor Cells [J] . Yuki Katayama, Yuichi Terasawa, Masashi Tachibana, BioMed research international . 2015,第13期

机译：病毒外衣壳蛋白的蛋白水解拆卸对于再缺乏病毒易感和再遗治 - 难治肿瘤细胞中的再遗治介导的I干扰素诱导至关重要
4. Nanoshell build-up onto non-fixed human red blood cells through the layer-by-layer self-assembly technique for their immunocamouflage [C] . Mansouri S., Merhi Y., Winnik F.M., IEEE Annual Northeast Bioengineering Conference . 2009

机译：通过逐层自组装技术将纳米壳堆积在未固定的人类红细胞上，从而产生免疫伪装
5. Immunocamouflage of Red Blood Cells by means of Layer-by-Layer Self-Assembly Technique for Medical Transfusion. [D] . Mansouri, Sania. 2011

机译：通过用于医学输液的逐层自组装技术对红细胞进行免疫伪装。
6. Proteolytic Disassembly of Viral Outer Capsid Proteins Is Crucial for Reovirus-Mediated Type-I Interferon Induction in Both Reovirus-Susceptible and Reovirus-Refractory Tumor Cells [O] . Yuki Katayama, Yuichi Terasawa, Masashi Tachibana, -1

机译：病毒外衣壳蛋白的蛋白水解拆卸对于呼肠孤病毒易感和呼肠孤病毒难治性肿瘤细胞中呼肠孤病毒介导的I型干扰素诱导至关重要。
7. Proteolytic Disassembly of Viral Outer Capsid Proteins Is Crucial for Reovirus-Mediated Type-I Interferon Induction in Both Reovirus-Susceptible and Reovirus-Refractory Tumor Cells [O] . Yuki Katayama, Yuichi Terasawa, Masashi Tachibana, 2015

机译：病毒外衣壳蛋白的蛋白水解拆卸对于可再缺乏病毒易感和难治性肿瘤细胞中的再遗治介导的I型干扰素诱导至关重要

Layer-by-layer assembly of viral capsid for cell adhesion.

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