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首页> 外文期刊>Acta biomaterialia >Micro-robotic deposition guidelines by a design of experiments approach to maximize fabrication reliability for the bone scaffold application.
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Micro-robotic deposition guidelines by a design of experiments approach to maximize fabrication reliability for the bone scaffold application.

机译：通过设计实验方法来实现微型机器人沉积指导，以最大程度地提高骨骼支架应用的制造可靠性。

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摘要

This work aims to facilitate the transition of micro-robotic deposition (muRD) technology from the research bench to a mass manufacturing environment. The bone scaffolding application is targeted; however, the evaluation process developed is applicable to multiple colloidal material systems, length scales, and structure architectures. A design of experiments (DoE) approach is used to develop statistical correlations between three manufacturing treatments (material calcination time, nozzle size, and deposition speed) and defined reliability metrics. All three selected treatments have a significant effect on structure quality. A longer material calcination time improves the deposition of internal features. Logically, a larger nozzle size decreases structural defects. However, an unexpected result is revealed by this study. Higher deposition speeds are shown to either significantly improve or have no effect on structure quality, permitting a decrease in manufacturing time without adverse consequences.
机译：这项工作旨在促进微型机器人沉积（muRD）技术从研究台到大规模生产环境的过渡。骨支架应用是针对性的;但是，开发的评估过程适用于多种胶体材料系统，长度标尺和结构体系结构。实验设计（DoE）方法用于开发三种制造处理（材料煅烧时间，喷嘴尺寸和沉积速度）与定义的可靠性指标之间的统计相关性。所有这三种选择的处理对结构质量都有显着影响。较长的材料煅烧时间可改善内部特征的沉积。从逻辑上讲，较大的喷嘴尺寸可减少结构缺陷。但是，这项研究揭示了出乎意料的结果。较高的沉积速度显示出可以显着改善结构质量或对结构质量没有影响，从而可以减少制造时间，而不会带来不利影响。

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