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首页> 外文期刊>Acta biomaterialia >Zinc-containing apatite layers on external fixation rods promoting cell activity.
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Zinc-containing apatite layers on external fixation rods promoting cell activity.

机译：外固定棒上的含锌磷灰石层可促进细胞活性。

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摘要

Zinc-containing apatite layers were successfully formed on commercially available anodically oxidized Ti external fixation rods using ZnCl(2)-containing supersaturated calcium phosphate solutions. With an increase in concentration of ZnCl(2) in the supersaturated calcium phosphate solutions, the amounts of zinc that precipitated on the Ti external fixation rods increased (from 0 to 0.195 + or - 0.020 microg cm(-2)); meanwhile, the amounts of calcium and phosphorus that precipitated on the Ti external fixation rods decreased (from 11.2 + or - 1.5 and 4.8 + or - 0.5 microg cm(-2) to 2.9 + or - 1.6 and 1.3 + or - 0.9 microg cm(-2), respectively). The zinc-containing apatite layers precipitated on the Ti external fixation rods caused a significant increase in fibroblastic proliferation, osteoblastic proliferation and differentiation in vitro. The Ti external fixation rods coated with zinc-containing apatite layers are expected to be more effective in accelerating the tissue regeneration around the surgical site than those coated with an apatite layer.
机译：使用含ZnCl（2）的过饱和磷酸钙溶液，在可商购获得的阳极氧化Ti外固定棒上成功形成了含锌的磷灰石层。随着过饱和磷酸钙溶液中ZnCl（2）浓度的增加，沉淀在Ti外固定棒上的锌量增加（从0增加到0.195 +或-0.020 microg cm（-2））;同时，沉淀在Ti外固定棒上的钙和磷的量减少了（从11.2 +或-1.5和4.8 +或-0.5 microg cm（-2）降至2.9 +或-1.6和1.3 +或-0.9 microg cm （-2））。沉淀在Ti外固定棒上的含锌磷灰石层导致体外成纤维细胞增殖，成骨细胞增殖和分化显着增加。预期涂覆有含锌磷灰石层的Ti外固定棒比涂覆磷灰石层的那些更能有效地促进手术部位周围的组织再生。

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