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首页> 外文期刊>Acta biomaterialia >Spatial variation of wear on Charite lumbar discs.
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Spatial variation of wear on Charite lumbar discs.

机译：Charite腰椎间盘磨损的空间变化。

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Total disc replacement (TDR) is a modern technique employed to treat degenerative disc disease that has the benefit of preserving motion compared with the clinically established spinal fusion. The wear performance of implants based on articulating designs is a key factor that determines their longevity and it is hypothesized that this will be the case for TDR devices. A detailed analysis of the surface of Charite lumbar disc replacements during simulated wear for five million cycles (MC), with inputs defined by the ISO18192-1 standard, is presented. After each million cycles the disc asperity heights, asperity curvature radii and their distributions on the surface of the core of the implant were determined at different locations. Two distinct areas on the surface of Charite polyethylene disc were identified based on the surface topography change during the wear simulation process. Within the area corresponding to the dome the initial roughness decreased, but after 2 MC the surface appeared to roughen with material build-up. More peripherally on the dome the surface roughness decreased after the first MC and remained constant. No effect was noticed on the rim. Furthermore, no statistical difference was noticed between the inferior and superior sides of the core of the disc. The study demonstrated that the wear on the two surfaces of the disc was uneven. This spatial variation is important in modelling the wear processes and providing strategies for reducing wear through enhanced design and modifications to the biotribological properties of the device.
机译：全椎间盘置换术（TDR）是一种用于治疗退行性椎间盘疾病的现代技术，与临床确定的脊柱融合术相比，它具有保持运动的优势。基于关节式设计的植入物的磨损性能是决定其使用寿命的关键因素，并且假设对于TDR设备而言，情况就是如此。提出了在模拟磨损进行五百万次循环（MC）期间进行Charite腰椎间盘置换术的表面的详细分析，其输入由ISO18192-1标准定义。在每百万次循环后，在不同位置确定椎间盘的凹凸高度，凹凸曲率半径及其在植入物核心表面的分布。根据磨损模拟过程中表面形貌的变化，确定了Charite聚乙烯圆盘表面上的两个不同区域。在与拱顶相对应的区域内，初始粗糙度降低，但是在2 MC之后，表面似乎随着材料的堆积而变粗糙。在第一次使用MC后，圆顶表面的外围粗糙度降低，并保持恒定。在轮辋上没有发现任何影响。此外，在椎间盘核心的下侧和上侧之间未发现统计学差异。研究表明，光盘两个表面的磨损是不均匀的。这种空间变化对于建模磨损过程并提供通过增强设计和修改设备的生物摩擦学特性来减少磨损的策略至关重要。

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