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首页> 外文期刊>Acta biomaterialia >Biocompatibility of sol-gel-derived titania-silica coated intramedullary NiTi nails.
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Biocompatibility of sol-gel-derived titania-silica coated intramedullary NiTi nails.

机译：溶胶-凝胶衍生的二氧化钛-二氧化硅涂层的镍钛髓内钉的生物相容性。

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摘要

We investigated bone response to sol-gel-derived titania-silica coated functional intramedullary NiTi nails that applied a continuous bending force. Nails 26 mm in length, either straight or with a radius of curvature of 28 or 15 mm, were implanted in the cooled martensite form from a proximal to distal direction into the medullary cavity of the right femur in 40 Sprague-Dawley rats. Body temperature restored the austenite form, causing the curved implants to generate a bending force on the bone. The femurs were examined after 24 weeks. Bone length measurements did not reveal any bowing or shortening of the bone in the experimental groups. The results from histomorphometry demonstrated that the stronger bending force, together with sol-gel surface treatment, resulted in more bone deposition around the implant and the formation of significantly less fibrous tissue. Straight intramedullary nails, even those with a titania-silica coating, were poorly attached when compared to the implants with a curved austenite structure.
机译：我们研究了骨骼对溶胶-凝胶衍生的二氧化钛-二氧化硅涂层的功能性髓内镍钛钉的反应，该钉施加了连续的弯曲力。将40毫米长的笔直或曲率半径为28或15毫米的钉子从近端到远端以冷却的马氏体形式植入40只Sprague-Dawley大鼠的右股骨髓腔中。体温恢复奥氏体形式，导致弯曲的植入物在骨骼上产生弯曲力。 24周后检查股骨。在实验组中，骨长的测量结果并未显示出任何弯曲或缩短的骨骼。组织形态计量学的结果表明，较强的弯曲力以及溶胶-凝胶表面处理可导致植入物周围更多的骨沉积，并显着减少纤维组织的形成。与具有弯曲奥氏体结构的植入物相比，笔直的髓内钉附着力差，即使是那些涂有二氧化钛-二氧化硅涂层的钉也是如此。

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