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首页> 外文期刊>Acta biomaterialia >Adhesion and cohesion in structures containing suspended microscopic polymeric films
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Adhesion and cohesion in structures containing suspended microscopic polymeric films

机译：在包含悬浮的微观聚合物薄膜的结构中的粘附力和内聚力

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This paper presents a novel technique for the characterization of adhesion and cohesion in suspended micro-scale polymeric films. The technique involves push-out testing with probes that are fabricated using focused ion beam techniques. The underlying stresses associated with different probe tip sizes were computed using a finite element model. The critical force for failure of the film substrate interface is used to evaluate adhesion, while the critical force for penetration of the film determines cohesion. When testing a standard material, polycarbonate, a shear strength of approximately 70 MPa was calculated using the Mohr-Coulomb theory. This value was shown to be in agreement with the results in the literature. The technique was also applied to the measurement of adhesion and cohesion in a model drug-eluting stent (the Nevo ? Sirolimus Eluting Coronary Stent) containing suspended microscopic polymeric films in metallic Co-Cr alloy reservoirs. The cohesive strength of the formulation was found to be comparable with that of plastics such as those produced by reaction injection molding and high-density polyethylene.
机译：本文提出了一种新技术，用于表征悬浮微尺度聚合物薄膜中的粘附和内聚。该技术包括使用聚焦离子束技术制造的探针进行推出测试。使用有限元模型计算了与不同探针大小相关的潜在应力。薄膜基材界面失效的临界力用于评估附着力，而薄膜渗透的临界力决定内聚力。当测试标准材料聚碳酸酯时，使用Mohr-Coulomb理论计算得出的剪切强度约为70 MPa。该值表明与文献中的结果一致。该技术还用于在药物洗脱模型支架（Nevo？Sirolimus洗脱冠状动脉支架）中测量粘附力和内聚力，该支架包含金属Co-Cr合金储层中的悬浮微观聚合物薄膜。发现该制剂的内聚强度与诸如通过反应注射成型和高密度聚乙烯生产的塑料的内聚强度相当。

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