Study of the complexation between Landomycin A and C-60 fullerene in aqueous solution

Prylutskyy Yu I.; Cherepanov V. V.; Kostjukov V. V.; Evstigneev M. P.; Kyzyma O. A.; Bulavin L. A.; Ivankov O.; Davidenko N. A.; Ritter U.

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Study of the complexation between Landomycin A and C-60 fullerene in aqueous solution

机译：水溶液中菌霉素A和C-60富勒烯之间的络合研究

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We report here the first investigation of the non-covalent complexation between C-60 fullerene and angucycline antibiotic Landomycin A. By means of various physico-chemical methods, including atomic force microscopy, dynamic light scattering, zeta-potential, small-angle neutron scattering and molecular modelling, it was shown that the obtained experimental data indirectly evidence complexation. This result provides scientific reasoning for further examination of the possible biological interaction between these agents on simultaneous administration in vivo and in vitro.

机译：我们在此报告首次调查C-60富勒烯和Anguc含胞菌抗生素型Landomiccin A的非共价络合。通过各种物理化学方法，包括原子力显微镜，动态光散射，Zeta - 电位，小角中子散射和分子建模，表明所获得的实验数据间接证据综合。该结果提供了科学推理，用于进一步检查这些药剂与体内同时施用这些药剂之间的可能生物相互作用。

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《RSC Advances》 |2016年第84期|共6页
作者
Prylutskyy Yu I.; Cherepanov V. V.; Kostjukov V. V.; Evstigneev M. P.; Kyzyma O. A.; Bulavin L. A.; Ivankov O.; Davidenko N. A.; Ritter U.;
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Taras Shevchenko Natl Univ Kyiv 64 Volodymyrska Str UA-01601 Kiev Ukraine;

NAS Ukraine Inst Phys Nauky Aven 46 UA-03680 Kiev Ukraine;

Sevastopol State Univ UA-299053 Sevastopol Ukraine;

Sevastopol State Univ UA-299053 Sevastopol Ukraine;

Taras Shevchenko Natl Univ Kyiv 64 Volodymyrska Str UA-01601 Kiev Ukraine;

Taras Shevchenko Natl Univ Kyiv 64 Volodymyrska Str UA-01601 Kiev Ukraine;

Taras Shevchenko Natl Univ Kyiv 64 Volodymyrska Str UA-01601 Kiev Ukraine;

Taras Shevchenko Natl Univ Kyiv 64 Volodymyrska Str UA-01601 Kiev Ukraine;

Ilmenau Univ Technol Weimarer Str 25 D-98693 Ilmenau Germany;

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中图分类化学;
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1. Study of the complexation between Landomycin A and C-60 fullerene in aqueous solution [J] . Prylutskyy Yu I., Cherepanov V. V., Kostjukov V. V., RSC Advances . 2016,第84期

机译：水溶液中菌霉素A和C-60富勒烯之间的络合研究
2. Molecular dynamics simulation study of the influence of cluster geometry on formation of C-60 fullerene clusters in aqueous solution [J] . Kim H, Bedrov D, Smith GD Journal of chemical theory and computation: JCTC . 2008,第2期

机译：团簇几何形状对水溶液中C-60富勒烯团簇形成影响的分子动力学模拟研究
3. Static and dynamic light scattering study of strong intermolecular interactions in aqueous solutions of PVP/C-60 complexes [J] . Sushko ML., Tenhu H., Klenin SI. Polymer: The International Journal for the Science and Technology of Polymers . 2002,第9期

机译：PVP / C-60配合物水溶液中强分子间相互作用的静态和动态光散射研究
4. Self-Organization of Pristine C_(60) Fullerene and its Complexes with Chemotherapy Drugs in Aqueous Solution as Promising Anticancer Agents [C] . Leonid A. Bulavin, Yuriy Prylutskyy, Olena Kyzyma, International Conference "Physics of Liquid Matter: Modern Problems" . 2018

机译：富勒烯的自我组织C_（60）富勒烯及其在水溶液中具有化疗药物的复合物，作为前途的抗癌剂
5. I. THE ELECTROCHEMISTRY OF NITRIC OXIDE AND A NITROUS ACID AT A MERCURY ELECTRODE IN AQUEOUS SOLUTIONS. II. ELECTROCHEMISTRY AND HYDROLYSIS KINETICS OF THE 2,2'-BIPYRIDINE COMPLEXES OF IRON(III) AND IRON(II); ELECTROCHEMICAL KINETIC PARAMETERS FOR SEVERAL IRON COMPLEXES. III. PROTON NUCLEAR MAGNETIC RESONANCE STUDIES OF URANIUM(IV)-ETHYLENE DIAMINETETRAACETIC ACID COMPLEXES IN AQUEOUS (DEUTERIUM-OXIDE) SOLUTIONS. [D] . EHMAN, DEWAYNE LEE. 1969

机译：I.水溶液中汞电极上一氧化二氮和亚硝酸的电化学二。铁（III）和铁（II）的2,2'-联吡啶络合物的电化学和水解动力学；多种铁络合物的电化学动力学参数。三，铀（IV）-水溶液（氧化氘）中铀（IV）-乙撑双氨基乙酸复合物的质子核磁共振研究
6. A Novel Nanoconjugate of Landomycin A with C60 Fullerene for Cancer Targeted Therapy: In Vitro Studies [O] . V. Bilobrov, V. Sokolova, S. Prylutska, 2019

机译：Landomycin A与C60富勒烯的新型纳米共轭物用于癌症靶向治疗的体外研究
7. Predicting the properties of a new class of host-guest complexes: C-60 fullerene and CB9 cucurbituril [O] . Fileti Eudes, Colherinhas Guilherme, Malaspina Thaciana 2014

机译：预测一类新型的宿主-客体复合物的性质：C-60富勒烯和CB 9葫芦素
8. NMR and ESR Studies of Solvation and Complex Formation In Aqueous and Non-Aqueous Solutions of Paramagnetic Ions [R] . Luz, Z. 1970

机译：顺磁性离子水溶液和非水溶液中溶剂化和络合物形成的NmR和EsR研究

Study of the complexation between Landomycin A and C-60 fullerene in aqueous solution

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