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Nanoparticles in sonodynamic therapy: state of the art review

机译：纳米粒子在铿ody性疗法：最先进的审查

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摘要

Sonodynamic therapy (SDT) is a novel therapeutic platform that involves a combination of low-intensity ultrasound and special bioagents called sonosensitizers. The application of nanoparticle technology substantially alters the concepts of traditional SDT. It has great potential to address many shortcomings which frequently trouble the clinical use of SDT, and paves the way for more effective yet safer therapeutic options. In this review, we systematically describe and compare the different individual types of nanoparticle that are being developed for SDT. Recent advances in the use of nanoparticles as sonosensitizers themselves or as carriers for sonosensitizer delivery are highlighted. Furthermore, potential limitations and future perspectives are also presented.
机译：SOONOGYNAMIC THERAPICATY（SDT）是一种新的治疗平台，涉及低强度超声和特殊生物胶原的组合，称为超声胶质剂。 纳米粒子技术的应用基本上改变了传统SDT的概念。 它有很大的潜力可以解决许多频繁的缺点，经常麻烦SDT的临床使用，并为更有效但更安全的治疗选择铺平道路。 在本文中，我们系统地描述并比较了正在为SDT开发的不同单独类型的纳米粒子。 突出的是使用纳米粒子作为超声溶胶的纳米粒子或用于超声源素递送的载体的近期进步。 此外，还提出了潜在的限制和未来的观点。

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  • 来源
    《RSC Advances》 |2016年第56期|共9页
  • 作者

    Xu Hongyan; Zhang Xia; Han Rubing; Yang Peimin; Ma Haifeng; Song Yan; Lu Zhichao; Yin Weidong; Wu XiangXia; Wang Hui;

  • 作者单位

    Peoples Hosp Linzi Dist Dept Pharm Linzi 255400 Shandong Peoples R China;

    Peoples Hosp Linzi Dist Dept Pharm Linzi 255400 Shandong Peoples R China;

    Peoples Hosp Linzi Dist Dept Pharm Linzi 255400 Shandong Peoples R China;

    Peoples Hosp Linzi Dist Dept Pharm Linzi 255400 Shandong Peoples R China;

    Peoples Hosp Linzi Dist Dept Pharm Linzi 255400 Shandong Peoples R China;

    Peoples Hosp Linzi Dist Dept Pharm Linzi 255400 Shandong Peoples R China;

    Peoples Hosp Linzi Dist Dept Pharm Linzi 255400 Shandong Peoples R China;

    Peoples Hosp Linzi Dist Dept Pharm Linzi 255400 Shandong Peoples R China;

    Peoples Hosp Linzi Dist Dept Pharm Linzi 255400 Shandong Peoples R China;

    Peoples Hosp Linzi Dist Dept Pharm Linzi 255400 Shandong Peoples R China;

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  • 正文语种 eng
  • 中图分类 化学;
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