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首页> 外文期刊>RSC Advances >Carbonyl iron coated with a sulfobetaine moiety as a biocompatible system and the magnetorheological performance of its silicone oil suspensions
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Carbonyl iron coated with a sulfobetaine moiety as a biocompatible system and the magnetorheological performance of its silicone oil suspensions

机译：涂有磺基替丹部分的羰基铁作为生物相容性系统和其硅油悬浮液的磁流变性能

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摘要

In this study, surface modification of carbonyl iron (CI) particles with sulfobetaine moieties (SBE) was performed by the silanization of activated CI to form stable CI-SBE particles. The modification led to a significant improvement of the thermo-oxidation stability and a negligible suppression of the magnetization of the particles, as revealed by thermogravimetric analysis and vibrating sample magnetometry, respectively. The effect of a magnetic field and temperature on the magnetorheological performance of particle suspensions was investigated using a rotational rheometer in order to clarify the suitability of these systems for the local embolization of blood veins. The suspension based on CI-SBE exhibited a pseudoplastic behaviour and a tunable yield stress in a range from 0.3-4 kPa at the normal human body temperature. Moreover, cell viability for fibroblasts and macrophages was examined via MTT assay, which revealed their suitability for the intended applications for the local embolization of blood veins.
机译：在该研究中，通过活性Ci的硅烷化进行磺基（CI）颗粒的表面改性，形成活化的Ci硅烷化以形成稳定的Ci-SbE颗粒。该改性导致热氧化稳定性的显着改善和可忽略的颗粒的磁化抑制，分别通过热重分析和振动样品磁体透露。使用旋转流变仪研究了磁场和温度对颗粒悬浮液的磁体性能的影响，以阐明这些系统对血尿局部栓塞的适用性。基于CI-SBE的悬浮液在正常人体温度下表现出假塑性行为和可调谐屈服应力，范围为0.3-4kPa。此外，通过MTT测定检查成纤维细胞和巨噬细胞的细胞活力，其揭示了它们适用于血尿局部栓塞的预期应用。

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  • 来源
    《RSC Advances》 |2016年第39期|共8页
  • 作者

    Mrlik Miroslav; Ilcikova Marketa; Cvek Martin; Pavlinek Vladimir; Zahoranova Anna; Kronekova Zuzana; Kasak Peter;

  • 作者单位

    Tomas Bata Univ Zlin Univ Inst Ctr Polymer Syst Trida T Bati 5678 Zlin 76001 Czech Republic;

    Slovak Acad Sci Polymer Inst Bratislava 84545 45 Slovakia;

    Tomas Bata Univ Zlin Univ Inst Ctr Polymer Syst Trida T Bati 5678 Zlin 76001 Czech Republic;

    Tomas Bata Univ Zlin Univ Inst Ctr Polymer Syst Trida T Bati 5678 Zlin 76001 Czech Republic;

    Slovak Acad Sci Polymer Inst Bratislava 84545 45 Slovakia;

    Slovak Acad Sci Polymer Inst Bratislava 84545 45 Slovakia;

    Qatar Univ Ctr Adv Mat POB 2713 Doha Qatar;

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  • 正文语种 eng
  • 中图分类 化学;
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