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首页> 外文期刊>RSC Advances >In situ calcium phosphate deposition in hydrogels of poly(acrylic acid)-polyacrylamide interpenetrating polymer networks
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In situ calcium phosphate deposition in hydrogels of poly(acrylic acid)-polyacrylamide interpenetrating polymer networks

机译：原位磷酸钙沉积在聚（丙烯酸）水凝胶中 - 聚酰胺互穿聚合物网络

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摘要

Interpenetrating networks of poly(acrylic acid) and polyacrylamide were used for the first time as templates for in situ calcium phosphate (CP) deposition in an attempt to mimic the naturally occurring biomineralization. The process of CP deposition was controlled by two main factors: the functionality and the overall crosslinking density of the IPNs' gels, both factors being varied via the IPNs' composition. The approach allowed the control of CP deposition in terms of amount, type and crystallite size. In this way the IPNs' potential as a template for controlled biomineralization was demonstrated. The obtained new inorganic-organic composite materials were characterized and their further potential in the fields of bone regeneration and substitution was revealed.
机译：作为原位磷酸钙（CP）沉积的模板首次使用聚（丙烯酸）和聚丙烯酰胺的互穿网络，以模拟天然存在的生物矿化。 CP沉积过程由两个主要因素控制：IPNS凝胶的功能和整体交联密度，这两个因素都通过IPNS的组成而变化。 该方法允许在量，型和微晶尺寸方面控制CP沉积。 以这种方式，证实了IPNS的电位作为受控生物矿化模板。 所得到的新的无机 - 有机复合材料的特征在于，并揭示了骨再生和取代领域的进一步潜力。

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