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首页> 外文期刊>RSC Advances >Understanding the effect of interaction among aeration, agitation and impeller positions on mass transfer during pullulan fermentation by Aureobasidium pullulans
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Understanding the effect of interaction among aeration, agitation and impeller positions on mass transfer during pullulan fermentation by Aureobasidium pullulans

机译：用金属硼烷淀粉蛋白淀粉发酵粉质发酵过程中曝气，搅拌和叶轮位置相互作用的影响

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摘要

Pullulan is a non-ionic, water-soluble homopolysaccharide produced via fermentation using Aureobasidium pullulans, a black yeast. The unique physicochemical properties of pullulan have made it a potential candidate for a diverse range of applications in various industrial sectors such as food, pharmaceutical, cosmetics, and biomedicine. Low yield and productivity are major challenges for the extensive commercialization of this biopolymer, and they are often found to be associated with poor mass transfer during the fermentative production of pullulan. The present study is an attempt to address this challenge by a unique multivariate approach. The interactive influence of air-flow rates, agitation speed and impeller spacing on volumetric mass transfer coefficient (k(L)a) was investigated using a statistical design. The design has demonstrated a unique correlation between mass transfer capabilities and process variables, whereas pullulan fermentation kinetics has revealed a dependence of microbial activity on kLa values in a bioprocess. Furthermore, the resultant mass transfer conditions were applied for pullulan production, which enhanced the productivity significantly (1.61 g L-1 h(-1)). These observations might help in obtaining improved mass transfer conditions for the economic production of pullulan.
机译：普林兰是一种非离子，水溶性均多糖，通过使用金青淀粉，黑酵母发酵生产。 Pullulan的独特物理化学特性使其成为各种工业部门各种应用的潜在候选者，例如食品，制药，化妆品和生物医学。低产率和生产率是这种生物聚合物广泛商业化的主要挑战，并且通常发现它们在Cullulan的发酵生产过程中与群众转移差。目前的研究是通过独特的多变量方法来解决这一挑战。使用统计设计研究了气流速率，搅拌速度和叶轮间距对体积传质系数（K（L）A）的交互式影响。该设计已经证明了传质能力与过程变量之间的独特相关性，而蛋白酶发酵动力学揭示了微生物活性在生物过程中对KLA值的依赖性。此外，将所得的传质条件施用于支链淀粉生产，这显着增强了生产率（1.61g L-1 h（-1））。这些观察可能有助于获得Pullulan经济生产的改善的传统转移条件。

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  • 来源
    《RSC Advances》 |2015年第49期|共11页
  • 作者

    Dixit Pooja; Mehta Ananya; Gahlawat Geeta; Prasad G. S.; Choudhury Anirban Roy;

  • 作者单位

    Inst Microbial Technol IMTECH CSIR Chandigarh 160036 India;

    Inst Microbial Technol IMTECH CSIR Chandigarh 160036 India;

    Inst Microbial Technol IMTECH CSIR Chandigarh 160036 India;

    Inst Microbial Technol IMTECH CSIR Chandigarh 160036 India;

    Inst Microbial Technol IMTECH CSIR Chandigarh 160036 India;

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  • 正文语种 eng
  • 中图分类 化学;
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