Facilely tuning the bioactivity of an orthopedic implant surface based on nanostructured polypyrrole/glycosaminoglycans

Zhu Zhaojin; Wang Yongping; Liu Jingfeng; Chen Gang; Zhu Yuan; Xu Xiangyang

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Facilely tuning the bioactivity of an orthopedic implant surface based on nanostructured polypyrrole/glycosaminoglycans

机译：基于纳米结构聚吡咯/糖氨基聚糖的骨科植入物表面的生物活性

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Herein, we report a facile approach to tune the bioactivity of orthopedic implants. The wettability of a Ti-6Al-4V orthopedic implant surface based on nanostructured polypyrrole (NPPy) doped with glycosaminoglycans (GAGs, major extracellular matrix components) can be controlled by in situ electrical stimulus, which was utilized to tune their bioactivity.

机译：在此，我们报告了一种沉积骨科植入物的生物活性的容易方法。基于含有糖胺聚糖（GAG，主要细胞外基质组分）的纳米结构聚吡咯（NPPY）的Ti-6AL-4V整形外科植入物表面的润湿性可以通过原位电刺激来控制，该刺激用于调节其生物活性。

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《RSC Advances》 |2015年第68期|共5页
作者
Zhu Zhaojin; Wang Yongping; Liu Jingfeng; Chen Gang; Zhu Yuan; Xu Xiangyang;
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作者单位

Shanghai Jiao Tong Univ Ruijin Hosp Sch Med Dept Orthoped Shanghai 200001 Peoples R China;

Shanghai Jiao Tong Univ Ruijin Hosp Sch Med Dept Orthoped Shanghai 200001 Peoples R China;

Shanghai Jiao Tong Univ Ruijin Hosp Sch Med Dept Orthoped Shanghai 200001 Peoples R China;

Shanghai Jiao Tong Univ North Ruijin Hosp Sch Med Dept Orthoped Shanghai 201801 Peoples R China;

Shanghai Jiao Tong Univ Ruijin Hosp Sch Med Dept Orthoped Shanghai 200001 Peoples R China;

Shanghai Jiao Tong Univ Ruijin Hosp Sch Med Dept Orthoped Shanghai 200001 Peoples R China;

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正文语种 eng
中图分类化学;
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1. Facilely tuning the bioactivity of an orthopedic implant surface based on nanostructured polypyrrole/glycosaminoglycans [J] . Zhu Zhaojin, Wang Yongping, Liu Jingfeng, RSC Advances . 2015,第68期

机译：基于纳米结构聚吡咯/糖氨基聚糖的骨科植入物表面的生物活性
2. Tuning nano-architectures and improving bioactivity of conducting polypyrrole coating on bone implants by incorporating bone-borne small molecules [J] . Liao Jingwen, Zhu Ye, Yin Zhaoyi, Journal of Materials Chemistry, B. materials for biology and medicine . 2014,第45期

机译：通过掺入骨载小分子来调整纳米体系结构并提高在骨植入物上进行聚吡咯涂层的生物活性
3. Mechanical characterization of anti-infectious, anti-allergic, and bioactive coatings on orthopedic implant surfaces [J] . Andreas Fritsche, Maximilian Haenle, Carmen Zietz, Journal of Materials Science . 2009,第20期

机译：整形外科植入物表面的抗感染，抗过敏和生物活性涂层的机械特性
4. Electrically-Controlled Penicillin/Streptomycin Release from Nanostructured Polypyrrole Coated on Titanium for Orthopedic Implants [C] . Sirinrath Sirivisoot, Rajesh A. Pareta, Thomas J. Webster Symposium C, Smart materials for smart devices and structures;Fall meeting of European Matericals Research Society; 20080915-19;20080915-19; Warsaw(PL);Warsaw(PL) . 2008

机译：电控青霉素/链霉素从用于钛涂层的纳米结构聚吡咯用于骨科植入物的释放
5. Engineered implantable nanotechnology sensor and electrically-controlled release of antibiotic and anti-inflammatory drugs using polypyrrole films electrodeposited on titanium for orthopedic implants. [D] . Sirivisoot, Sirinrath. 2009

机译：经过设计的可植入纳米技术传感器，并使用电沉积在钛上的聚吡咯膜对骨科植入物进行电控释放抗生素和抗炎药。
6. Tuning nano-architectures and improving bioactivity of conducting polypyrrole coating on bone implants by incorporating bone-borne small molecules [O] . Jingwen Liao, Ye Zhu, Zhaoyi Yin, -1

机译：通过掺入骨载小分子来调整纳米体系结构并提高在骨植入物上进行聚吡咯涂层的生物活性
7. Study on Construction of the Electro-bioactive Coating on the Surface of Bone Implant Materials based on the Electrically Conductive Polypyrrole (PPy) Nanowires [O] . 穆静 2010

机译：基于导电聚吡咯（PPy）纳米线的骨植入材料表面电生物活性涂层的构建研究

Facilely tuning the bioactivity of an orthopedic implant surface based on nanostructured polypyrrole/glycosaminoglycans

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