Silver(I) ions modulate the stability of DNA duplexes containing cytosine, methylcytosine and hydroxymethylcytosine at different salt concentrations

Wang Yong; Ritzo Brandon; Gu Li-Qun

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Silver(I) ions modulate the stability of DNA duplexes containing cytosine, methylcytosine and hydroxymethylcytosine at different salt concentrations

机译：银（I）离子调节含有胞嘧啶，甲基胞嘧啶和羟甲基甲基胞嘧啶的DNA双链体以不同盐浓度的稳定性

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Silver(I) ions can stabilize cytosine-cytosine, cytosine (C)-methylcytosine (5mC) and cytosine-hydroxymethylcytosine (5hmC) mismatched-base pairs. While cytosine modifications regulate DNA stability to regulate cellular functions, silver ions can modulate the stability of C-C, C-5mC and C-5hmC containing DNA duplexes in a salt concentration dependent manner.

机译：银（I）离子可以稳定胞嘧啶 - 胞嘧啶，胞嘧啶（C） - 甲基胞嘧啶（5MC）和胞嘧啶 - 羟甲基胞嘧啶（5HMC）错配碱对。虽然胞嘧啶修饰调节DNA稳定性来调节细胞功能，但是银离子可以以盐浓度依赖性方式调节含有DNA双链体的C-C，C-5MC和C-5HMC的稳定性。

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来源
《RSC Advances》 |2015年第4期|共4页
作者
Wang Yong; Ritzo Brandon; Gu Li-Qun;
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Univ Missouri Dept Biol Engn Columbia MO 65211 USA;

Univ Missouri Dept Biol Engn Columbia MO 65211 USA;

Univ Missouri Dept Biol Engn Columbia MO 65211 USA;

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正文语种 eng
中图分类化学;
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1. Silver(I) ions modulate the stability of DNA duplexes containing cytosine, methylcytosine and hydroxymethylcytosine at different salt concentrations [J] . Wang Yong, Ritzo Brandon, Gu Li-Qun RSC Advances . 2015,第4期

机译：银（I）离子调节含有胞嘧啶，甲基胞嘧啶和羟甲基甲基胞嘧啶的DNA双链体以不同盐浓度的稳定性
2. Specific interactions between silver(I) ions and cytosine-cytosine pairs in DNA duplexes [J] . Akira Ono, Shiqi Cao, Humika Togashi, Chemical Communications . 2008,第39期

机译：DNA双链体中银离子与胞嘧啶-胞嘧啶对之间的特异性相互作用
3. Rates of formation and thermal stabilities of RNA:DNA and DNA:DNA duplexes at high concentrations of formamide [J] . James Casey, Norman Davidson Nucleic acids research . 1977,第5期

机译：高浓度甲酰胺下RNA：DNA和DNA：DNA双链体的形成速率和热稳定性
4. Targeted profiling of 5-(hydroxy)methylcytosine in genomic DNA from human livers: Next-generation sequencing of target enriched DNA reveals unexpectedly high interindividual variability of cytosine methylation and hydroxymethylation [C] . Ivanov Maxim, Ingelman-Sundberg Magnus, Kals Mart, IEEE International Conference on Bioinformatics and Biomedicine . 2014

机译：人类肝脏基因组DNA中5-（羟）甲基胞嘧啶的靶向分析：富含靶DNA的下一代测序揭示了胞嘧啶甲基化和羟甲基化的意料之外的高度个体差异
5. NMR studies of I. Photodamaged DNA duplexes, II. Sodium concentrations in septic mouse and III. Two iron chelates as potential brain MRI contrast agents. [D] . Li, Wei. 2001

机译：I.光损坏的DNA双链体的NMR研究，II。败血症小鼠和III中的钠浓度。两种铁螯合物可作为潜在的脑部MRI造影剂。
6. Silver(I) ions modulate the stability of DNA duplexes containing cytosine methylcytosine and hydroxymethylcytosine at different salt concentrations [O] . Yong Wang, Brandon Ritzo, Li-Qun Gu -1

机译：银（I）离子可调节不同盐浓度下含胞嘧啶甲基胞嘧啶和羟甲基胞嘧啶的DNA双链体的稳定性
7. Silver(i) ions modulate the stability of DNA duplexes containing cytosine, methylcytosine and hydroxymethylcytosine at different salt concentrations [O] . Yong Wang, Brandon Ritzo, Li-Qun Gu 2015

机译：银（I）离子调节含有胞嘧啶，甲基胞嘧啶和羟甲基甲基胞嘧啶的DNA双链体以不同盐浓度的稳定性

Silver(I) ions modulate the stability of DNA duplexes containing cytosine, methylcytosine and hydroxymethylcytosine at different salt concentrations

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