首页> 外文期刊>RSC Advances >Adhesion and bending rigidity-mediated wrapping of carbon nanotubes by a substrate-supported cell membrane
【24h】

Adhesion and bending rigidity-mediated wrapping of carbon nanotubes by a substrate-supported cell membrane

机译:粘附和弯曲刚性介导的碳纳米管用基材支撑的细胞膜包裹

获取原文
获取原文并翻译 | 示例
           

摘要

A fundamental understanding of the adhesive interaction between carbon nanotubes (CNTs) and a cell membrane is essential for the design and potential applications of CNT-based drug delivery systems, gene carries, as well as biosensors. In this work, we set up a theoretical model to explore the wrapping effect of a substrate-supported membrane on CNTs, taking the deformation of CNTs into consideration. Our results show that the competition between the membrane bending stiffness and the CNT-membrane adhesion strength induces a double-edged effect on the stability of a single CNT wrapped by a substrate-supported membrane, that is, the membrane can facilitate the laying down and collapse of the CNT due to its bending rigidity, while it tends to maintain the upright and open shape of the CNT as a result of the CNT-membrane adhesion. The phase boundary for the open and collapsed configurations due to this competition can be well described by a simple analytical model. Furthermore, the competition can also result in the transition of the membrane between adhering to and detaching from the substrate in the system of two widely spaced CNTs covered by a substrate-supported cell membrane, which is consistent with experimental observations.
机译:对碳纳米管(CNT)和细胞膜之间的粘合剂相互作用的基本理解对于CNT的药物递送系统,基因以及生物传感器,基于CNT的药物递送系统的设计和潜在应用是必不可少的。在这项工作中,我们建立了一个理论模型,以探讨基板支撑膜对CNT的包装效果,考虑CNT的变形。我们的研究结果表明,膜弯曲刚度和CNT膜粘合强度之间的竞争导致对由基材负载的膜包裹的单个CNT的稳定性的双刃效应,即,膜可以促进铺设和铺设由于其弯曲刚度,CNT塌陷,而由于CNT膜粘附,因此倾向于保持CNT的直立和开口形状。由于这种竞争引起的开放和折叠配置的相位边界可以通过简单的分析模型进行很好地描述。此外,竞争还可以导致膜在粘附和拆卸之间的膜中的转变,其在由基板支撑的细胞膜覆盖的两个广泛间隔的CNT的系统中,这与实验观察一致。

著录项

  • 来源
    《RSC Advances》 |2015年第54期|共8页
  • 作者单位

    Dalian Univ Technol Fac Vehicle Engn &

    Mech Dept Engn Mech State Key Lab Struct Anal Ind Equipment Dalian 116024 Peoples R China;

    Dalian Univ Technol Fac Vehicle Engn &

    Mech Dept Engn Mech State Key Lab Struct Anal Ind Equipment Dalian 116024 Peoples R China;

    Dalian Univ Technol Fac Vehicle Engn &

    Mech Dept Engn Mech State Key Lab Struct Anal Ind Equipment Dalian 116024 Peoples R China;

    Dalian Univ Technol Fac Vehicle Engn &

    Mech Dept Engn Mech State Key Lab Struct Anal Ind Equipment Dalian 116024 Peoples R China;

  • 收录信息
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 化学;
  • 关键词

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号