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首页> 外文期刊>Acta Dermato-Venereologica >Cutaneous microdialysis of uric acid level in the dermis: modification of in vitro recovery.
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Cutaneous microdialysis of uric acid level in the dermis: modification of in vitro recovery.

机译:真皮中尿酸水平的皮肤微透析:体外恢复的修饰。

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摘要

Cutaneous microdialysis is a new tool for direct sampling and real-time monitoring in dermatological research. However, its use in general laboratory practice poses several problems, one of which is determination of the relative recovery of the target material. Uric acid, one of the major antioxidants in the skin, was analysed using cutaneous microdialysis in 11 healthy subjects. Two methods for in vitro recovery were adopted, one in which a standard solution of uric acid was used and another in which serum was used. Although differences between the two methods were found, it is suggested that establishing the in vitro recovery using serum might be a simple approach for microdialysis.
机译:皮肤微透析是皮肤病学研究中直接采样和实时监测的新工具。但是,其在一般实验室实践中的使用带来了几个问题,其中之一是确定目标物质的相对回收率。尿酸是皮肤中的主要抗氧化剂之一,使用皮肤微透析对11位健康受试者进行了分析。采用两种体外恢复方法,一种使用标准的尿酸溶液,另一种使用血清。尽管发现了两种方法之间的差异,但建议使用血清建立体外恢复可能是进行微透析的简单方法。

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