Using biomaterials to modulate chemotactic signaling for central nervous system repair

Kassondra Hickey; Sarah E Stabenfeldt

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Using biomaterials to modulate chemotactic signaling for central nervous system repair

机译：使用生物材料来调节中枢神经系统修复的趋化信号

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Chemotaxis enables cellular communication and movement within the body. This review focuses on exploiting chemotaxis as a tool for repair of the central nervous system (CNS) damaged from injury and/or degenerative diseases. Chemokines and factors alone may initiate repair following CNS injury/disease, but exogenous administration may enhance repair and promote regeneration. This review will discuss critical chemotactic molecules and factors that may promote neural regeneration. Additionally, this review highlights how biomaterials can impact the presentation and delivery of chemokines and growth factors to alter the regenerative response.

机译：趋化性使蜂窝通信和体内的运动能够。本综述侧重于利用趋化性作为修理中枢神经系统（CNS）损坏的趋势和/或退行性疾病的工具。单独的趋化因子和因素可能会在CNS损伤/疾病之后修复，但外源给药可能会增强修复和促进再生。该审查将讨论可能促进神经再生的关键趋化分子和因素。此外，该综述突出了生物材料如何影响趋化因子和增长因素的呈现和交付，以改变再生反应。

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来源
《Biomedical materials》 |2018年第4期|共14页
作者
Kassondra Hickey; Sarah E Stabenfeldt;
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作者单位

School of Biological and Health Systems Engineering Arizona State University Tempe AZ United States of America;

School of Biological and Health Systems Engineering Arizona State University Tempe AZ United States of America;

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原文格式 PDF
正文语种 eng
中图分类医用一般科学;
关键词
chemotaxis; stroke; traumatic brain injury; spinal cord injury; drug delivery; central nervous system;

机译：趋化性;中风;创伤性脑损伤;脊髓损伤;药物递送;中枢神经系统;

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1. Using biomaterials to modulate chemotactic signaling for central nervous system repair [J] . Kassondra Hickey, Sarah E Stabenfeldt Biomedical materials . 2018,第4期

机译：使用生物材料来调节中枢神经系统修复的趋化信号
2. Subcutaneous Transplantation of Neural Precursor Cells in Experimental Autoimmune Encephalomyelitis Reduces Chemotactic Signals in the Central Nervous System [J] . Ravanidis Stylianos, Poulatsidou Kyriaki Nepheli, Lagoudaki Roza, Stem cells translational medicine. . 2015,第12期

机译：在实验性自身免疫性脑脊髓炎中神经前体细胞的皮下移植减少中枢神经系统趋化信号
3. Subcutaneous Transplantation of Neural Precursor Cells in Experimental Autoimmune Encephalomyelitis Reduces Chemotactic Signals in the Central Nervous System [J] . Stylianos Ravanidis, Kyriaki Nepheli Poulatsidou, Roza Lagoudaki, Stem cells translational medicine. . 2015,第12期

机译：在实验性自身免疫性脑脊髓炎中神经前体细胞的皮下移植减少了中枢神经系统的趋化信号
4. Stem Cell Delivery to Promote Repair in the Central Nervous System [C] . Molly S. Shoichet, Brian Ballios, Howard Kim, Society for Biomaterials fall symposium 2012.;vol. 34. . 2012

机译：干细胞输送以促进中枢神经系统的修复
5. Colony -stimulating factor-1 receptor-signaling in the development of the skeletal and the central nervous systems [D] . Nandi, Sayan 2009

机译：骨骼和中枢神经系统发育中的集落刺激因子-1受体信号转导
6. Using Biomaterials to Modulate Chemotactic Signaling for Central Nervous System Repair [O] . Kassondra Hickey, Sarah E. Stabenfeldt -1

机译：使用生物材料调节趋化信号以修复中枢神经。
7. Extracellular matrix based biomaterials for central nervous system tissue repair: the benefits and drawbacks [O] . Sarka Kubinova 2017

机译：基于细胞外基质的生物材料用于中枢神经系统组织修复：优点和缺点

Using biomaterials to modulate chemotactic signaling for central nervous system repair

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