High-Resolution Atomic Force Microscopy of DNA

D. V. Klinov; T. V. Neretina; V. V. Prokhorov

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High-Resolution Atomic Force Microscopy of DNA

机译：DNA的高分辨率原子力显微镜显微镜

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摘要

A method using high resolution atomic force microscopy for imaging DNA has been elaborated. Using super-sharp probes and modified graphite as support for molecule adsorption, DNA molecule images were obtained whose resolution made possible the observation of their fine structure with repeated helical motifs. The method can be used to visualize individual spread molecules of single-stranded DNA.

机译：已经详细阐述了使用高分辨率原子力显微镜进行成像DNA的方法。使用超尖探针和改性石墨作为对分子吸附的支持，获得了DNA分子图像，其分辨率使得它们具有重复的螺旋基序的细结构观察。该方法可用于可视化单链DNA的单独扩散分子。

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来源
《Biochemistry》 |2009年第10期|共5页
作者
D. V. Klinov; T. V. Neretina; V. V. Prokhorov;
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作者单位

Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry Russian Academy of Sciences ul. Miklukho-Maklaya 16/10 117997 Moscow Russia;

Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry Russian Academy of Sciences ul. Miklukho-Maklaya 16/10 117997 Moscow Russia;

Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry Russian Academy of Sciences ul. Miklukho-Maklaya 16/10 117997 Moscow Russia;

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原文格式 PDF
正文语种 eng
中图分类生物化学;
关键词
AFM; high resolution; DNA; scanning probes; HOPG;

机译：AFM;高分辨率;DNA;扫描探针;HOPG;

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1. High-Resolution Imaging of Plasmid DNA in Liquids in Dynamic Mode Atomic Force Microscopy Using a Carbon Nanofiber Tip [J] . Masashi Kitazawa, Shuichi Ito, Akira Yagi, Japanese journal of applied physics . 2011,第8Issue4期

机译：动态模式原子力显微镜使用碳纳米纤维尖端对液体中质粒DNA的高分辨率成像
2. High-Resolution Atomic Force Microscopy of DNA [J] . D. V. Klinov, T. V. Neretina, V. V. Prokhorov Biochemistry . 2009,第10期

机译：DNA的高分辨率原子力显微镜显微镜
3. High-resolution atomic force microscopy of duplex and triplex DNA molecules [J] . Dmitry Klinov, Benjamin Dwir, Eli Kapon Nanotechnology . 2007,第22期

机译：双链和三链DNA分子的高分辨率原子力显微镜
4. Atomic force microscopy of DNA-colloidal gold and DNA-protein complexes [C] . Luming Niu, Iowa State Univ., Ames, Advances in DNA Sequencing Technology . 1993

机译：DNA胶体金和DNA蛋白质复合物的原子力显微镜
5. Forced translocation of DNA hairpins through a tight molecular nanopore studied by atomic force microscopy in force-spectroscopy mode. [D] . Ashcroft, Brian Alan. 2007

机译：DNA发夹通过紧密分子纳米孔的强制移位，通过原子力显微镜在力谱模式下研究。
6. Dialysis Purification of Integrase-DNA Complexes Provides High-Resolution Atomic Force Microscopy Images: Dimeric Recombinant HIV-1 Integrase Binding and Specific Looping on DNA [O] . Tatsuaki Tsuruyama, Tonau Nakai, Rei Ohmori, 2010

机译：整合酶-DNA复合物的透析纯化可提供高分辨率的原子力显微镜图像：二聚重组HIV-1整合酶结合和DNA上的特异性环
7. Dialysis Purification of Integrase-DNA Complexes Provides High-Resolution Atomic Force Microscopy Images: Dimeric Recombinant HIV-1 Integrase Binding and Specific Looping on DNA. [O] . Tsuruyama Tatsuaki, Nakai Tonau, Ohmori Rei, 2013

机译：整合酶-DNA复合物的透析纯化可提供高分辨率的原子力显微镜图像：二聚体重组HIV-1整合酶结合和DNA的特异性环化。

High-Resolution Atomic Force Microscopy of DNA

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