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Impacts of dynamic degradation on the morphological and mechanical characterisation of porous magnesium scaffold

机译：动态降解对多孔镁支架形态和力学表征的影响

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This study employs a computational approach to analyse the impact of morphological changes on the structural properties of biodegradable porous Mg subjected to a dynamic immersion test for its application as a bone scaffold. Porous Mg was immersed in a dynamic immersion test for 24, 48, and 72h. Twelve specimens were prepared and scanned using micro-CT and then reconstructed into a 3D model for finite element analysis. The structural properties from the numerical simulation were then compared to the experimental values. Correlations between morphological parameters, structural properties, and fracture type were then made. The relative losses were observed to be in agreement with relative mass loss done experimentally. The degradation rates determined using exact (degraded) surface area at particular immersion times were on average 20% higher than the degradation rates obtained using original surface area. The dynamic degradation has significantly impacted the morphological changes of porous Mg in volume fraction, surface area, and trabecular separation, which in turn affects its structural properties and increases the immersion time.
机译：本研究采用计算方法来分析形态变化对生物降解多孔MG的结构性能的影响，其作为骨支架施用动态浸渍试验。将多孔Mg浸入24,48和72h的动态浸渍试验中。使用微型CT制备并扫描12个样品，然后重建为有限元分析的3D模型。然后将来自数值模拟的结构性能与实验值进行比较。然后制备形态参数，结构性能和骨折类型之间的相关性。观察到相对损失与实验进行的相对质量损失一致。使用特定浸入时间确定的精确（降解）表面积测定的降解速率平均高于使用原始表面积获得的降解速率高出20％。动态降解显着影响了体积分数，表面积和小梁分离中多孔Mg的形态变化，这又影响其结构性质并增加浸入时间。

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