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首页> 外文期刊>Biopreservation and biobanking >Attitudes and Perceptions of Cancer Patients Toward Biospecimen Donation for Cancer Research: A Cross-Sectional Survey Among Chinese Cancer Patients
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Attitudes and Perceptions of Cancer Patients Toward Biospecimen Donation for Cancer Research: A Cross-Sectional Survey Among Chinese Cancer Patients

机译：癌症研究患者癌症研究的态度与看法：中国癌症患者的横截面调查

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Background: High-quality biospecimen collection from consented patients is crucial for cancer research activities. Patients' attitudes and willingness toward specimen donation influence high-quality biospecimen collection for cancer research activities. Methods: We carried out a cross-sectional study among randomly selected patients from 11 cancer departments of Tianjin Medical University Cancer Institute and Hospital between August 2014 and August 2015. A total of 784 patients were included to complete a 30-item self-administered survey. We evaluated the patients' willingness to consider providing leftover samples and additional samples for cancer research purposes. Results: Among 784 patients, 683 (87.1%) and 653 (83.3%) were willing to donate leftover tissue and surplus blood after diagnosis, respectively. Six hundred thirty-one (80.5%) were favorably disposed to consider donating both tissue and blood samples for future cancer research. Female patients showed less willingness to donate biospecimens or related clinical data for research. First-hospitalized or older patients were less willing to provide leftover biospecimens or additional blood samples or even clinical data for research. By contrast, patients with a higher education level were more likely to donate leftover tissues after biopsy or surgery for research activities. Conclusions: Most Chinese cancer patients were willing to consider donating blood and tissue samples for cancer research. Several factors, including age, gender, first hospitalization, and education level, can influence their willingness to donate biospecimens. We need to provide proper education to increase understanding of patients in biobanking activities. Impact: This study provides novel empirical data on the likelihood of donating surplus and additional biospecimens and clinical health information among Chinese cancer patients.
机译：背景：来自同意患者的高质量生物开发系列对癌症研究活动至关重要。患者对标本捐赠的态度和愿意影响癌症研究活动的高质量生物选择收集。方法：我们在2014年8月和2015年8月期间对天津医科大学癌症研究所和医院11癌癌症研究所和医院的随机选择患者进行了横截面研究。包括784名患者，以完成30件物品的自我管理调查。我们评估患者愿意考虑提供剩余的样本和其他样本的癌症研究目的。结果：784名患者中，683名（87.1％）和653名（83.3％）分别均愿意在诊断后捐赠剩余的组织和剩余血液。有利于六百三十一（80.5％），以考虑捐赠组织和血液样本以供未来的癌症研究。女性患者表现出捐赠生物开发或相关的研究临床数据的意愿。第一家住院或老年患者不太愿意提供剩余的生物起草或额外的血液样本甚至是研究的临床数据。相比之下，高等教育水平的患者更有可能在活检或手术后捐赠剩余的组织进行研究活动。结论：大多数中国癌症患者愿意考虑捐献血液和组织样本的癌症研究。几个因素，包括年龄，性别，首次住院和教育水平，可以影响他们捐赠生物起草的意愿。我们需要提供适当的教育，以提高对生物管理活动患者的理解。影响：本研究提供了关于捐赠剩余和额外的生物学和额外生物学的可能性和中国癌症患者的临床健康信息的新型实证数据。

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