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首页> 外文期刊>Biopreservation and biobanking >Qatar Biobank: A Paradigm of Translating Biobank Science into Evidence-Based Health Care Interventions
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Qatar Biobank: A Paradigm of Translating Biobank Science into Evidence-Based Health Care Interventions

机译：卡塔尔Biobank：将Biobank Science转化为基于证据的医疗保健干预的范例

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摘要

Biobank science is progressively becoming indispensable for the development of novel diagnostic tools in health care, by pairing standardized high-quality biological samples, phenotypic, and omics data required to best characterize the underlying biological mechanisms of response to therapy and survival. Qatar Biobank (QBB), Qatar's National Repository Centre for biological samples and health information, aligning with these endeavors, has developed a strategic framework to enable biobanking science that can be transformed into tangible health care diagnostic tools. In this concept, QBB works closely with multidisciplinary stakeholders: (1) governmental authorities (n = 2), (2) health providers (n = 3), (3) academic institutions (n = 28), (4) other research institutions (n = 6), and (5) the Qatar National Research Fund, by providing data and biospecimens to research projects. The local community organizes campaigns through social media and interactive events, spreading the concept of biobanking to inform and encourage people to participate. Up to now, QBB has recruited up to 30% of the targeted population and collaborated with 35 national and international research entities contributing to more than 170 research projects. QBB is referring about 53% of its participants to the Hamad general hospital through the integrated information system, revealing the need of new health screening approaches for public health policy makers. QBB contributed to the development of a customized genetic screening microarray tailored to the Qatari population that will be used in research as well as for the screening of variants of medical relevance in Qatar, promoting precision medicine in Qatar's health care system. The QBB strategic plan is a paradigm for the optimal utilization of resources, infrastructure, and investments engaging the local authorities and the research entities, and committing them to data sharing and working together toward the discovery of evidence-based health care interventions.
机译：通过配对标准化的高质量生物样品，表型和最佳响应治疗和存活的基础生物学机制，Biobank Science逐渐成为医疗保健中的新型诊断工具的发展不可或缺的诊断工具。卡塔尔Biobank（QBB），卡塔尔的生物样本和健康信息储存中心，与这些努力保持一致，已经制定了一个战略框架，以实现可以转化为有形的医疗保健诊断工具的生物汉科学。在这一概念中，QBB与多学科利益相关者密切合作：（1）政府当局（N = 2），（2）卫生供应商（N = 3），（3）学术机构（N = 28），（4）其他研究机构（n = 6），并通过向研究项目提供数据和生物学，Qatar国家研究基金。当地社区通过社交媒体和互动事件组织竞选活动，传播生物库的概念来告知并鼓励人们参加。截至目前，QBB招聘了高达目标人口的30％，并与35个国家和国际研究实体合作，为170多项研究项目提供了贡献。 QBB通过综合信息系统将其参与者的53％的参与者称为Hamad综合医院，揭示了对公共卫生政策制定者的新健康筛查方法的需求。 QBB促进了针对Qatari人口定制的定制遗传筛查微阵列的开发，这些Qatari人口将用于研究以及筛查卡塔尔在卡塔尔的医学相关性，促进卡塔尔医疗保健系统的精确药物。 QBB战略计划是最佳利用资源，基础设施和投资，从事地方当局和研究实体的投资，并使他们致力于数据分享，共同努力发现基于证据的医疗保健干预措施。

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