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首页> 外文期刊>Biopreservation and biobanking >Usage Data and Scientific Impact of the Prospectively Established Fluid Bioresources at the Hospital-Based MedUni Wien Biobank
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Usage Data and Scientific Impact of the Prospectively Established Fluid Bioresources at the Hospital-Based MedUni Wien Biobank

机译：在基于医院Meduni Wien Biobank的前瞻性建立的流体生物资源的使用数据和科学影响

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Background and Aim: It is increasingly recognized that biomedical research has serious reproducibility issues, which could be overcome at least in part by standardized processing of biomaterials. Therefore, professional biobanks have emerged, positively influencing sample and data quality. However, quantitative data about a biobank's contribution to published results are still hard to find, although they could serve as valuable benchmark figures for the community. We therefore aimed to report usage data from the MedUni Wien Biobank facility regarding its prospective fluid cohorts. Methods: Input and access statistics and publication output were reported for the years 2010-2017. Performance dynamics were tested by correlation analyses according to Spearman. Additionally, virtual costs per sample were calculated. Results: The amount of annually collected aliquots rose significantly from 68,500 in 2010 to 151,966 in 2017 (p=0.015), although no further increase was recorded after 2012 (p=0.266). In the same period, the quotient of requested to stored aliquots increased from 3.5% to 6.1% (p=0.001), as the yearly number of requested aliquots nearly quadrupled from 2401 to 9342. Likewise, the number of published research articles per year to which the MedUni Wien Biobank contributed increased from 2 (total impact factor: 8.6) in 2010 to 16 (total impact factor: 69.0) in 2017, resulting in a total of 69 identified publications. Currently, the biobank operates at 15- to 20-fold overproduction, leading to virtual costs per accessed sample of approximate to Euro20. Conclusion: The reported usage data might serve as a benchmark for other hospital-integrated biobanks, and implies that academic biobanks are able to produce considerable scientific impact at comparable moderate costs.
机译：背景和目的：越来越认识到，生物医学研究具有严重的可重复性问题，这可以至少部分地通过对生物材料的标准化加工来克服。因此，专业的BioBanks已经出现了，积极影响样品和数据质量。然而，关于BioBank对公布结果贡献的定量数据仍然很难找到，尽管它们可以作为社区的有价值的基准数据。因此，我们旨在向其前瞻性流体队列的Meduni Wien Biobank设施报告使用数据。方法：报告了2010 - 2017年的输入和访问统计信息和出版物输出。根据Spearman，通过相关分析测试性能动态。另外，计算每个样本的虚拟成本。结果：每年收集的等分试样的量显着增加2017年的68,500至151,966（P = 0.015），尽管2012年后没有进一步增加（P = 0.266）。在同一时期，所需储存等分试样的商量从3.5％增加到6.1％（p = 0.001），因为从2401到9342年的请求等分试样的年度数量几乎二次。同样，每年发表的研究文章的数量2010年至16日至16日（总影响因素：69.0），Meduni Wien Biobank的贡献增加到2010年（总影响因素：69.0），导致总共69个已识别出版物。目前，BIOBANK在15至20倍的过量生产中运行，导致每个访问的近似欧洲20个样本的虚拟成本。结论：报告的使用数据可能是其他医院综合生物人数的基准，意味着学术生物汉能够以可比的中等成本产生相当大的科学影响。

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