Interleukin 15 is a growth factor for human thymocytes with preferential effect on CD8(+)cells.

Thulesen S; Nielsen M; Petersen TR; Holst Nissen-M; Odum N; Ropke C

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Interleukin 15 is a growth factor for human thymocytes with preferential effect on CD8(+)cells.

机译：白介素15是人类胸腺细胞的生长因子，对CD8（+）细胞具有优先作用。

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The effects of IL-15, as compared to IL-2, on growth of human thymocytes has been evaluated. Expression of comparable amounts of receptor chains was found on IL-2 and IL-15 cultured thymocytes, as well as comparable receptor signalling. However, IL-15 was superior to IL-2 in promoting CD8(+)thymocyte growth, whereas CD4(+)cells proliferated to a higher extent in IL-2 cultures. CD4(+)8(+)and CD4(-)8(-)thymocytes expanded equally well in both culture types. Copyright 2000 Academic Press.

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《Cytokine》 |2000年第6期|共5页
作者
Thulesen S; Nielsen M; Petersen TR; Holst Nissen-M; Odum N; Ropke C;
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正文语种 eng
中图分类细胞生物学;
关键词
CD8-Positive T-Lymphocytes; Interleukin-15; interleukin-15-receptor; Interleukin-2; CD8阳性T淋巴细胞; 白细胞介素15;

机译：CD8-Positive T-Lymphocytes;Interleukin-15;interleukin-15-receptor;Interleukin-2;CD8阳性T淋巴细胞;白细胞介素15;

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1. Interleukin 15 is a growth factor for human thymocytes with preferential effect on CD8(+)cells. [J] . Thulesen S, Nielsen M, Petersen TR, Cytokine . 2000,第6期

机译：白介素15是人类胸腺细胞的生长因子，对CD8（+）细胞具有优先作用。
2. Regulatory T Cells in the Control of Autoimmunity: the Essential Role of Transforming Growth Factor β and Interleukin 4 in the Prevention of Autoimmune Thyroiditis in Rats by Peripheral CD4+CD45RC? Cells and CD4+CD8? Thymocytes [J] . Benedict Seddon, Don Mason The Journal of Experomental Medicine . 1999,第2期

机译：调节性T细胞在自身免疫控制中的作用：转化生长因子β和白介素4在预防外周CD4 + CD45RC大鼠自身免疫性甲状腺炎中的重要作用？细胞和CD4 + CD8？胸腺细胞
3. Interleukin-15/interleukin-15R alpha complexes promote destruction of established tumors by reviving tumor-resident CD8+ T cells. [J] . Epardaud M, Elpek KG, Rubinstein MP, Cancer research: The official organ of the American Association for Cancer Research, Inc . 2008,第8期

机译：白细胞介素15 /白细胞介素-15Rα复合物通过使驻留在肿瘤中的CD8 + T细胞恢复活力来促进已建立肿瘤的破坏。
4. The influence of ALA-mediated photodynamic therapy on secretion of selected growth factors, interleukins and S100 protein (s100) by colon cancer cells in vitro. [C] . Aleksandra Kawczyk-Krupka, Zenon Czuba, Wojciech Latos, International Photodynamic Association World Congress;Society of Photo-Optical Instrumentation Engineers;International Photodynamic Association . -1

机译：ALA介导的光动力疗法对结肠癌细胞体外分泌某些生长因子，白介素和S100蛋白（s100）的影响。
5. The Effects of Insulin-Like Growth Factors on Human G292 Osteosarcoma Cells. [D] . AlHousami, Thabet Mahmood. 2017

机译：胰岛素样生长因子对人G292骨肉瘤细胞的影响。
6. Thymocyte-Thymic Epithelial Cell Interaction Leads to High-Level Replication of Human Immunodeficiency Virus Exclusively in Mature CD4+ CD8− CD3+ Thymocytes: a Critical Role for Tumor Necrosis Factor and Interleukin-7 [O] . L. Chêne, M.-T. Nugeyre, E. Guillemard, 1999

机译：胸腺细胞胸腺上皮细胞相互作用导致人类免疫缺陷病毒的高水平复制完全在成熟的CD4 + CD8- CD3 +胸腺细胞中：肿瘤坏死因子和白介素7的关键作用。
7. Thymocyte-Thymic Epithelial Cell Interaction Leads to High-Level Replication of Human Immunodeficiency Virus Exclusively in Mature CD4 + CD8 − CD3 + Thymocytes: a Critical Role for Tumor Necrosis Factor and Interleukin-7 [O] . L. Chêne, M.-T. Nugeyre, E. Guillemard, 1999

机译：胸腺细胞上皮细胞相互作用引起了人类免疫缺陷病毒的高水平复制，专门在成熟的CD4 + CD8 - CD3 +胸腺细胞中：肿瘤坏死因子和白细胞介素-7的关键作用
8. Effect of Interleukin-1beta and Tumor Necrosis Factor-alpha on Gene Expression in Human Endothelial Cells. [R] . Zhao, B., Stavchansky, S. A., Bowden, R. A., 2003

机译：白细胞介素-1β和肿瘤坏死因子-α对人内皮细胞基因表达的影响。

Interleukin 15 is a growth factor for human thymocytes with preferential effect on CD8(+)cells.

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