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首页> 外文期刊>Biocontrol Science >Stable Antimicrobial Activity Achieved via Immobilization of Quaternary Ammonium Chloride on Hair
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Stable Antimicrobial Activity Achieved via Immobilization of Quaternary Ammonium Chloride on Hair

机译：通过固定季氯化铵在头发上实现的稳定抗菌活性

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摘要

Dandruff and underarm malodor are caused by microorganisms. Personal hygiene products that contain various types of antimicrobial agents are available and are used for the prevention and alleviation of these conditions. However, their effects are not significant and often do not last long. Working toward a solution, hair was treated with thioglycolic acid, a reducing agent, and then with [2- (acryloyloxy) ethyl] trimethylammonium chloride to covalently bond and immobilize quaternary ammonium chloride (QAC) to hair shafts. Fourier transform infrared analysis confirmed the bonding of QAC. Time-kill assays were performed to evaluate the antimicrobial activities against two yeast strains responsible for dandruff, two bacterial strains responsible for underarm malodor, and two typical bacterial skin microflora strains. The time- kill assays revealed the antimicrobial effects of QAC against all tested microorganisms. Washing with detergents decreased the antimicrobial effects compared to hair not washed with detergent. This method could potentially replace personal hygiene products, such as shampoos and antiperspirants, which act as antimicrobial agents in the prevention and alleviation of dandruff and underarm malodor.
机译：头皮屑和腋下恶臭是由微生物引起的。含有各种类型的抗微生物剂的个人卫生产品可用于预防和缓解这些条件。然而，他们的效果并不重要，并且通常不会持续很长时间。致溶液，用巯基乙酸，还原剂处理毛发，然后用[2-（丙烯酰氧基）乙基]三甲基氯化铵，共价键合并将季铵氯化铵（QAC）固定到毛发轴上。傅里叶变换红外分析证实了QAC的键合。进行时间杀死测定以评估对抗头皮屑的两种酵母菌株的抗微生物活性，负责腋下的恶臭的两种细菌菌株，以及两个典型的细菌皮肤微生物微生物菌株。时间杀死测定揭示了QAC对所有测试微生物的抗微生物作用。与未用洗涤剂洗涤的毛发相比，用洗涤剂洗涤降低了抗微生物作用。这种方法可能会替代个人卫生产品，如洗发剂和止汗剂，该产品充当抗菌药物在预防和减轻头皮屑和腋下恶臭的抗微生物剂。

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