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Genetic variability at promoters of IL-18 (pro-) and IL-10 (anti-) inflammatory gene affects susceptibility and their circulating serum levels: An explorative study of prostate cancer patients in North Indian populations

机译:IL-18(促-)和IL-10(抗-)炎性基因启动子的遗传变异性影响易感性及其循环血清水平:北印度人群前列腺癌患者的一项探索性研究

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摘要

Inflammation is an important hallmark of all types of cancers with a well-established role in carcinogenesis. The net inflammatory response is determined by the balance between pro- and anti-inflammatory cytokines, the levels of which may be affected by the genetic make-up.
机译:炎症是所有类型的癌症的重要标志,在致癌作用中具有公认的作用。净炎症反应取决于促炎和抗炎细胞因子之间的平衡,其水平可能受到基因组成的影响。

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