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首页> 外文期刊>British journal of ophthalmology >An update on the modern management of paediatric uveitis
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An update on the modern management of paediatric uveitis

机译：关于儿科葡萄炎现代管理的更新

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摘要

Uveitis in children and young people (CYP) is often painless, chronic and persistent. It is an often silent blinding condition. Uveitis can be isolated or develop as a manifestation of a systemic disease. Due to the symptomless nature, it can present late with advanced ocular comorbidities such as band keratopathy, hypotony, cataracts. Inadequate control of the eye inflammation can result in permanent and severe ocular complications, structural damage and visual loss. One of the most common systemic associations is juvenile idiopathic arthritis where uveitis has a cumulative incidence of approximately 10%–14% (though wide variation in incidence is reported) after 5 years. Appropriately targeted uveitis screening is recommended to continue for at least 7 years in some subgroups. Paediatric uveitis poses multiple diagnostic and therapeutic challenges. Clinical manifestation and disease course may differ significantly from adult-onset uveitis. However, some CYP are still managed by adult specialists alone, without the opportunity for the prompt use of National Health Service England approved therapy. Optimal management of paediatric uveitis requires a multidisciplinary approach involving coordinated working of different specialities and healthcare professionals. This article highlights the evidence-based practice for the contemporary management of paediatric uveitis to readers in different specialities who may come across this condition. It raises awareness of early systemic treatment aiming to achieve early and complete disease inactivity thereby improving the chances of a long-term positive outcome.
机译：儿童和青少年（CYP）葡萄膜炎通常是无痛，慢性和持续的。这是一种经常沉默的致盲条件。葡萄膜炎可以被分离或发展作为全身疾病的表现。由于症状性质，它可以呈现晚期，晚期眼镜疗法，如乐队角膜病变，低间断，白内障。对眼睛炎症的控制不足会导致永久性和严重的眼部并发症，结构损伤和视觉损失。最常见的全身关联之一是幼年特发性关节炎，葡萄膜炎的累积发生率约为10％-14％（虽然在5年后报告了广泛的发生率。建议在某些亚组中持续至少7年的适当靶向葡萄膜炎。小儿葡萄膜炎造成多种诊断和治疗挑战。临床表现和疾病课程可能与成人发作葡萄膜炎有显着差异。但是，一些CYP仍由成人专家单独管理，而无需迅速使用国家卫生服务英国批准的治疗。儿科葡萄膜炎的最佳管理需要多学科方法，涉及不同专业和医疗保健专业人员的协调工作。本文突出了基于证据的基于循证葡萄儿儿科葡萄炎对读者的实践，不同专业可能会遇到这种情况。它提高了对早期全身治疗的认识，旨在实现早期和完整的疾病不活动，从而提高了长期阳性结果的机会。

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