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首页> 外文期刊>British journal of ophthalmology >New modifications of Swedish ROP guidelines based on 10-year data from the SWEDROP register
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New modifications of Swedish ROP guidelines based on 10-year data from the SWEDROP register

机译：基于瑞典册注册的10年数据的瑞典ROP指南的新修改

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Background/aims During the last decade, improved neonatal care has resulted in increased survival of the most immature infants and improved health of more mature infants. We hypothesise that this has affected incidence and treatment of retinopathy of prematurity (ROP), enabling guidelines for screening to be modified. Methods In Sweden, all infants with gestational age (GA) at birth <= 30 weeks are screened for ROP. Results are registered in a web-based register, Swedish National ROP Register, with a coverage rate of 97%. Incidence of ROP and frequency of treatment, aspects on natural course of ROP and number of examinations, are calculated in relation to GA at birth in infants born during 2008-2017. Results Of 7249 infants, 31.9% (2310) had ROP and 6.1% (440) were treated. No infant with GA 30 weeks was treated. Incidence of ROP remained similar, but frequency of treatment increased (p=0.023). Over time, GA and birth weight were reduced in infants with ROP and with treated ROP. In the most immature infants, postmenstrual age was lower and postnatal age was higher when any ROP and stage 3 ROP were first detected (p<0.001). At treatment, postmenstrual but not postnatal age of the infant was associated with GA (p<0.001). During the 10-year period, 46 038 examinations were performed. Conclusion Modification of Swedish guidelines is proposed, including only infants with a GA of <30 weeks and postponing the first examination with 1 week in infants with GA 26-29 weeks. This would spare many infants from stressful examinations and reduce eye examinations with at least 20%.
机译：背景/目的在过去十年中，改善的新生儿护理导致最不成熟的婴儿的存活率增加，并改善了更成熟的婴儿的健康状况。我们假设这对早期（ROP）的疗法感染和治疗具有患有率和治疗，使得筛选准则进行修改。方法在瑞典，患有胎儿（GA）的所有婴儿在出生时<= 30周被筛选。结果在基于网络的寄存器中注册，瑞典国家ROP注册，覆盖率为97％。 ROP发病率和治疗频率，关于ROP自然过程的方面和考试的数量，在2008 - 2017年出生的婴儿出生时与GA有关。结果为7249名婴儿，31.9％（2310），治疗了6.1％（440）。没有治疗GA 30周的婴儿。 ROP的发病率保持相似，但治疗频率增加（p = 0.023）。随着时间的推移，幼儿园和出生体重在婴儿和伴有的婴儿和治疗的ROP减少。在最不成熟的婴儿中，当检测到任何ROP和第3阶段的ROP时，后续年龄较低，后期较高（P <0.001）。在治疗中，婴儿的后期但不是产后年龄与GA相关（P <0.001）。在10年期间，进行了46个038次考试。结论提出了瑞典指引的修改，包括仅婴儿<30周的婴儿，并在26-29周内用1周推迟第一次检查。这将使许多来自压力检查的婴儿，并减少至少20％的眼睛检查。

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