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Severe preeclampsia: Association of genes polymorphisms and maternal cytokines production in Brazilian population

机译:严重先兆子痫:巴西人群中基因多态性与母体细胞因子产生的关联

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Introduction: Preeclampsia (PE) is a multi-system disorder of pregnancy characterized by hypertension and proteinuria. Healthy pregnancy is associated with a controlled inflammatory process, which is exacerbated in PE in response to excessive placental stimuli. Gene expression levels can affect inflammation and immune regulation. It is known that differences in cytokine allele frequencies amongst populations may contribute to difference in the incidence of several diseases.
机译:简介:先兆子痫(PE)是一种以高血压和蛋白尿为特征的多系统妊娠疾病。健康的怀孕与可控的炎症过程相关,在过度的胎盘刺激下,PE会加剧炎症。基因表达水平可以影响炎症和免疫调节。众所周知,人群中细胞因子等位基因频率的差异可能会导致几种疾病的发病率差异。

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