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Opioid-free anesthesia

机译:无阿片内麻醉

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摘要

Opioid-free anesthesia (OFA) is emerging as a new stimulating research perspective. The rationale to propose OFA is based on the aim to avoid the negative impact of intraoperative opioid on a patient's postoperative outcomes and also on the physiology of pathways involved in intraoperative nociception. It is based on the concept of multimodal anesthesia. OFA has been shown to be feasible but the literature is still scarce on the clinically meaningful benefits for patients as well as on the side effects and/or complications that might be associated with it. This review focused first on the physiology of nociception, the reasons for using or not using opioids during anesthesia, and then on the literature reporting evidence-based proofs of benefits/risks associated with OFA.
机译:无阿片类麻醉(OFA)是一种新的刺激研究视角。 提出的理由是基于旨在避免术中阿片类药物对患者术后结果的负面影响以及术中术语的途径的生理学。 它是基于多模式麻醉的概念。 OFA已被证明是可行的,但文献仍然缺乏对患者的临床有意义的益处以及可能与之相关的副作用和/或并发症。 本综述首先侧重于伤害伤害的生理学,在麻醉期间使用或不使用阿片类药物的原因,然后在文献中报告基于证据的福利/风险证据。

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