...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Best practice & research:Clinical obstetrics & gynaecology >Is sperm DNA fragmentation a useful test that identifies a treatable cause of male infertility?
【24h】

Is sperm DNA fragmentation a useful test that identifies a treatable cause of male infertility?

机译：精子DNA碎片是一种有用的测试，鉴定了男性不孕症的可治疗原因吗？

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

The present-day laboratory methods of sperm analysis are a poor predictor of reproductive outcome, and for many years it has been clear that newer and better tests are required. Although many such tests have been proposed, only those which determine sperm DNA quality are still being considered. Of these, several tests of sperm DNA fragmentation are available, although there is presently no consensus about the most appropriate test, the best test specimen (fresh or washed sperm) or what level of fragmentation is of clinical concern. Moreover, although several strategies have been proposed to reduce DNA fragmentation, there is no universal approach and few randomised trials have tested these in a clinical context. As such, most professional bodies do not presently support the use of sperm DNA fragmentation tests, and it is clear that large randomised trials are still required to further evaluate their clinical effectiveness. (C) 2018 Elsevier Ltd. All rights reserved.
机译：本日的精子分析的实验室方法是生殖结果的差，多年来已经清楚了，需要更新，更好的测试。 尽管已经提出了许多这样的测试，但只考虑确定精子DNA质量的那些。 其中，有几种精子DNA片段化的测试可获得，尽管目前没有关于最合适的测试，最佳试样（新鲜或洗涤的精子）或临床关注程度的临床关注的共识。 此外，虽然已经提出了几种策略来减少DNA碎片，但没有普遍的方法，并且很少有随机试验在临床环境中测试这些试验。 因此，大多数专业机构都没有目前支持使用精子DNA碎片试验，并且很明显，仍然需要大规模的随机试验来进一步评估它们的临床效果。 （c）2018年elestvier有限公司保留所有权利。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号