Combinatorial Haplo-deficient tumor suppression in 7q-Deficient myelodysplastic syndrome and acute myeloid leukemia

WillB.; SteidlU.

首页> 外文期刊>Cancer Cell >Combinatorial Haplo-deficient tumor suppression in 7q-Deficient myelodysplastic syndrome and acute myeloid leukemia

【24h】

Combinatorial Haplo-deficient tumor suppression in 7q-Deficient myelodysplastic syndrome and acute myeloid leukemia

机译：7Q缺陷型髓细胞增生综合征和急性髓性白血病的组合Haplo缺乏肿瘤抑制

获取原文

获取原文并翻译 | 示例

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

Heterozygous deletions of chromosome 7 are frequent in myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML). In this issue of Cancer Cell, Chen and colleagues identify MLL3 as a novel haplo-insufficient tumor suppressor on 7q that, in combination with NF1 suppression and TP53 deficiency, mediates MDS and AML phenotypes in mouse and human systems.

机译：染色体7的杂合缺失在髓细胞增生综合征（MDS）和急性髓性白血病（AML）中经常出现。在这个问题中，陈和同事们将MLL3鉴定为新的HLO不足的肿瘤抑制剂，在7Q中，与NF1抑制和TP53缺乏组合，在小鼠和人体系统中介导MDS和AML表型。

著录项

来源
《Cancer Cell》 |2014年第5期|共3页
作者
WillB.; SteidlU.;
展开▼
作者单位

Department of Cell Biology Albert Einstein College of Medicine/Montefiore Medical Center New York;

Department of Cell Biology Albert Einstein College of Medicine/Montefiore Medical Center New York;

展开▼
收录信息
原文格式 PDF
正文语种 eng
中图分类肿瘤学;
关键词

相似文献

外文文献
中文文献
专利

1. Combinatorial Haplo-deficient tumor suppression in 7q-Deficient myelodysplastic syndrome and acute myeloid leukemia [J] . WillB., SteidlU. Cancer Cell . 2014,第5期

机译：7Q缺陷型髓细胞增生综合征和急性髓性白血病的组合Haplo缺乏肿瘤抑制
2. Suppression of farnesyltransferase activity in acute myeloid leukemia and myelodysplastic syndrome: current understanding and recommended use of tipifarnib. [J] . Epling Burnette PK, Loughran TP Jr Expert opinion on investigational drugs . 2010,第5期

机译：急性髓细胞性白血病和骨髓增生异常综合症中法尼基转移酶活性的抑制：目前对替非法尼的理解和推荐使用。
3. Suppression of the DNA damage response in acute myeloid leukemia versus myelodysplastic syndrome [J] . S Boehrer, L Adès, N Tajeddine, Oncogene . 2009,第22期

机译：抑制急性髓性白血病与髓细胞增强综合征的DNA损伤反应
4. Ras gene mutation in acute myeloid leukemia and Myelodysplastic syndromes: a meta-analysis of its occurrence and prognostic relevance [C] . Cheng Jingru, Wang Peng, Zhang Tai, International Conference on Advanced Materials and Computer Science . 2016

机译：RAS基因突变在急性髓性白血病和髓细胞增强综合征中：荟萃分析其发生和预后相关性
5. Myelodysplastic Syndrome Progression to Acute Myeloid Leukemia at the Stem Cell Level [D] . Chen, Jiahao. 2018

机译：在干细胞水平上骨髓增生异常综合征进展为急性髓细胞性白血病
6. Suppression of Farnesyltransferase Activity in Acute Myeloid Leukemia and Myelodysplastic Syndrome: Current Understanding and Recommended Use of Tipifarnib [O] . P.K. Epling-Burnette, Thomas P. Loughran Jr. -1

机译：抑制急性髓性白血病和髓细胞增生综合征的法呢基转移酶活性：目前的理解和推荐使用Tipifarnib
7. Combinatorial Haplo-Deficient Tumor Suppression in 7q-Deficient Myelodysplastic Syndrome and Acute Myeloid Leukemia [O] . Will Britta, Steidl Ulrich 2014

机译：7q缺乏骨髓增生异常综合症和急性髓细胞白血病的组合单倍体缺乏肿瘤抑制

Combinatorial Haplo-deficient tumor suppression in 7q-Deficient myelodysplastic syndrome and acute myeloid leukemia

摘要

著录项

相似文献

相关主题

期刊订阅