The interleukin-6/Janus kinase/STAT3 pathway in pleomorphic adenoma and carcinoma ex pleomorphic adenoma of the lacrimal gland

Andreasen Simon; Heegaard Steffen; Grauslund Morten; Homoe Preben

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The interleukin-6/Janus kinase/STAT3 pathway in pleomorphic adenoma and carcinoma ex pleomorphic adenoma of the lacrimal gland

机译：白细胞介素6 / Janus激酶/ STAT3通路在泪腺多形性腺瘤和癌前多形性腺瘤中的作用

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PurposePleomorphic adenoma (PA) is the most common tumour of the lacrimal gland, but very little is known about its biology. It has a tendency to recur and an ability to transform into the high-grade malignancy carcinoma ex pleomorphic adenoma (ca-ex-PA), which is also largely unexplored. In this study, we examine the expression of the interleukin-6/Janus kinase/STAT3 (IL-6/JAK/STAT3) pathway components in PA and ca-ex-PA.

机译：目的多形性腺瘤（PA）是泪腺最常见的肿瘤，但对其生物学知之甚少。它有复发的趋势，并有能力转化为高度恶性的癌，即多形性腺瘤（ca-ex-PA），这在很大程度上尚待探索。在这项研究中，我们检查了PA和ca-ex-PA中白介素6 / Janus激酶/ STAT3（IL-6 / JAK / STAT3）途径组分的表达。

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来源
《Acta ophthalmologica》 |2016年第8期|共7页
作者
Andreasen Simon; Heegaard Steffen; Grauslund Morten; Homoe Preben;
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正文语种 eng
中图分类眼科学;
关键词
carcinoma ex pleomorphic adenoma; Interleukin-6; JAK; lacrimal gland; pleomorphic adenoma; STAT3;

机译：多形性腺瘤;白介素6;JAK;泪腺;多形性腺瘤;STAT3;

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1. The interleukin-6/Janus kinase/STAT3 pathway in pleomorphic adenoma and carcinoma ex pleomorphic adenoma of the lacrimal gland [J] . Andreasen Simon, Heegaard Steffen, Grauslund Morten, Acta ophthalmologica . 2016,第8期

机译：白细胞介素6 / Janus激酶/ STAT3通路在泪腺多形性腺瘤和癌前多形性腺瘤中的作用
2. Immunohistochemical features of carcinoma ex pleomorphic adenoma and pleomorphic adenoma in the lacrimal gland [J] . Ping Zhang1, Li-Juan Tang1, Huan-Huan Gao1, 国际眼科杂志：英文版 . 2019,第008期

机译：泪腺多形性腺瘤和多形性腺瘤的免疫组织化学特征
3. Recurrent rearrangements of the PLAG 1 PLAG PLAG 1 and HMGA 2 HMGA HMGA 2 genes in lacrimal gland pleomorphic adenoma and carcinoma ex pleomorphic adenoma [J] . Andreasen Simon, Holstein Sarah L., Hom?e Preben, Acta ophthalmologica . 2018,第7期

机译：Plag 1 plag pleomorphic腺瘤和癌in pleomorphic腺瘤中的Plag 1 plag plag 1和hmga 2 hmga hmga 2基因的复发重排。
4. Radiomics-Based Differentiation of Pleomorphic Adenomas and Warthin Tumors of Salivary Glands [C] . Henry J. Areiza-Laverde, Norberto Malpica-González, Beatriz Brea, Conference on International Symposium on Medical Information Processing and Analysis;Society of Photo-Optical Instrumentation Engineers . 2020

机译：基于放射学的涎腺多形性腺瘤和沃辛瘤的分化
5. Transforming growth factor beta one and colorectal neoplasia: A case-control examination of adenoma and carcinoma in Hawaii. [D] . Saltzman, Barbara S. 2007

机译：转化生长因子β1和结直肠肿瘤：夏威夷腺瘤和癌的病例对照检查。
6. Immunohistochemical features of carcinoma ex pleomorphic adenoma and pleomorphic adenoma in the lacrimal gland [O] . Ping Zhang, Li-Juan Tang, Huan-Huan Gao, 2019

机译：泪腺多形性腺瘤和多形性腺瘤的免疫组织化学特征
7. The interleukin-6/Janus kinase/STAT3 pathway in pleomorphic adenoma and carcinoma ex pleomorphic adenoma of the lacrimal gland [O] . Simon Andreasen, Steffen Heegaard, Morten Grauslund, 2016

机译：白细胞介素-6 / Janus激酶/ stat3肺炎腺癌和癌症患者的癌症腺癌

The interleukin-6/Janus kinase/STAT3 pathway in pleomorphic adenoma and carcinoma ex pleomorphic adenoma of the lacrimal gland

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