• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Cardiology >Rheumatic Mitral Stenosis: Long-Term Follow-Up of Adult Patients with Nonsevere Initial Disease
【24h】

Rheumatic Mitral Stenosis: Long-Term Follow-Up of Adult Patients with Nonsevere Initial Disease

机译：风湿性二尖瓣狭窄：非耐性初期疾病的成年患者的长期随访

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Introduction: There is no consensus regarding the natural history of rheumatic mitral stenosis (MS) among adults presenting with nonsevere disease. This study aims to describe the progression of stenosis among adult rheumatic MS patients, to identify predictive factors for progression, and to assess the incidence of complications. Methods: A retrospective cohort analysis was performed among patients with rheumatic MS treated at a single center. Eighty-five patients were included with mild to moderate MS, >= 30 years old on initial echocardiography. Demographics, medical history, echocardiographic reports over at least 10 years, and related complications were obtained from a computerized database. Results: Over a period of 13.1 +/- 2.38 years, 75 patients (88%) had no significant progression in stenosis severity. The final echocardiographic assessment demonstrated 2 groups with a significant difference between them regarding the mitral valve area (1.58 +/- 0.44 vs. 1.1 +/- 0.26 cm(2), p = 0.001) and mean valvular pressure gradient (6.27 +/- 2.52 vs. 8.5 +/- 2.69 mm Hg, p = 0.01). Patients with indolent MS (group A) were compared to patients with progressive disease (group B), and a higher percent of Bedouin patients were found in group B (OR 8.036, p = 0.015). No significant differences were found in other parameters. Complications including atrial fibrillation, cerebral ischemic events, and impaired right ventricle function, although frequent, were not statistically different between the groups. Conclusions: An indolent natural progression of rheumatic MS was observed in our study. Despite this finding, it still has potentially deleterious effects. Bedouin patients have a higher risk for progressive disease.
机译：介绍：在具有非耐性疾病的成人中，对风湿二尖瓣狭窄（MS）的自然病史没有达成共识。本研究旨在描述成人风湿MS患者狭窄的进展，以确定进展的预测因素，并评估并发症的发生率。方法：在单一中心处理的风湿MS患者中进行回顾性群组分析。将八十五名患者含有轻度至中等MS，> = 30岁在初始超声心动图中。人口统计数据，医学史，超声心动图报告至少10年，以及从计算机数据库获得相关的并发症。结果：在13.1 +/- 2.38岁的时间内，75名患者（88％）在狭窄严重程度中没有显着进展。最终的超声心动图评估显示2组，它们之间有关于二尖瓣面积的显着差异（1.58 +/- 0.44与1.1 +/- 0.26cm（2），p = 0.001）和平均瓣膜压梯度（6.27 +/- 2.52与8.5 +/- 2.69 mm hg，p = 0.01）。将惰性MS（A组）患者与渐进性疾病（B组）的患者进行比较，并且在B组（或8.036，P = 0.015）中发现了较高百分比的贝都宾患者。在其他参数中没有发现显着的差异。在包括心房颤动，脑缺血性事件和受损的右心室功能的并发症虽然频繁，但在组之间没有统计学意义。结论：在我们的研究中观察到风湿MS的惰性自然进展。尽管这一发现，它仍然存在有害影响。贝都宾患者对进步性疾病的风险较高。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号