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首页> 外文期刊>Cardiology >Management and Outcome of Ventricular Septal Rupture Complicating Acute Myocardial Infarction: What Is New in the Era of Percutaneous Intervention?
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Management and Outcome of Ventricular Septal Rupture Complicating Acute Myocardial Infarction: What Is New in the Era of Percutaneous Intervention?

机译：心室间隔破裂的管理和结果使急性心肌梗死复杂：经皮干预时代的新增功能是什么？

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Background: Postinfarction ventricular septal rupture (PI-VSR) is a rare but devastating complication of acute myocardial infarction (AMI). Risk stratification in the acute phase is crucial for decision-making, and this study analyzed the risk factors for early mortality and the effects of various management options on the outcome of PI-VSR patients in the era of percutaneous intervention. Methods: A total of 96 patients with PI-VSR were identified and divided into an acute-phase survivor group (n = 46, survived >= 2 weeks after admission) and a nonsurvivor group (n = 50, died within 2 weeks after admission). Percutaneous closure was considered in acute-phase survivors. Patients were followed up for a mean 47 (quartiles 15-71) months by clinical visit or telephone interview. Results: The overall acute-phase (i.e., = 2 weeks, 20 underwent interventional occlusion and the procedure was successful in 19. Percutaneous closure in the acute-phase survivor group improved the immediate (21% in-hospital mortality rate) and long-term (53% mortality) outcomes. Conclusions: Patients with PI-VSR are at a high risk of acute-phase mortality. Female sex and severe cardiac dysfunction at admission are linked with a high rate of acute-phase deaths. Percutaneous closure in acute-phase survivors results in favorable short-and long-term benefits for PI-VSR patients. (C) 2019 S. Karger AG, Basel
机译：背景：Postinfrount心室隔膜破裂（PI-VSR）是急性心肌梗死（AMI）的罕见但破坏性并发症。急性期风险分层对决策至关重要，这项研究分析了早期死亡率的危险因素和各种管理方案对皮-VSR患者在经皮干预时期的结果的影响。方法：将96例PI-VSR患者鉴定并分为急性期幸存小组（N = 46，存活> =入院后2周）和非尿道组（N = 50，入院后2周内死亡）。在急性期幸存者中考虑经皮闭合。通过临床访问或电话采访，患者随访平均47个月（四分之一15-71）个月。结果：总体急性阶段（即，= 2周，20次进行介入闭塞和该程序成功19.急性期幸存者组的经皮闭合改善了直接（21％的住院死亡率）和长期术语（53％死亡率）结果。结论：PI-VSR患者处于急性期死亡率的高风险。入院的女性和严重的心脏功能障碍与高急性期死亡率相关联。经皮闭合-phase幸存者导致PI-VSR患者的良好短期和长期效益。（c）2019年S. Karger AG，巴塞尔

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