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首页> 外文期刊>Cardiology >Etiology of Atrial Functional Mitral Regurgitation: Insights from Transthoracic Echocardiography in 159 Consecutive Patients with Atrial Fibrillation and Preserved Left Ventricular Ejection Fraction
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Etiology of Atrial Functional Mitral Regurgitation: Insights from Transthoracic Echocardiography in 159 Consecutive Patients with Atrial Fibrillation and Preserved Left Ventricular Ejection Fraction

机译：心房功能二尖瓣流反流的病因：159例心房颤动患者进行Transthoracic超声心动图的见解，并保存左心室喷射分数

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Background:Left atrial (LA) dilatation in patients with atrial fibrillation (AF) can induce functional mitral regurgitation (MR) despite a preserved left ventricular ejection fraction (LVEF). The purpose of this study was to investigate the etiology of this functional MR.Methods:We retrospectively examined clinical and echocardiographic data from 5,202 consecutive cases that underwent transthoracic echocardiography. AF appeared in 544 patients, and we selected 159 with AF and LVEF >= 50% after excluding patients with other underlying heart diseases.Results:Significant (moderate or greater) degrees of functional MR were seen in 13 (8.2%) patients and were more frequently seen in patients with an AF duration of >10 years than in others (27 vs. 4%,p= 0.0057). Multiple regression analysis revealed that both the LA dimension index and the left ventricular (LV) systolic dimension index were independent determinants of the MR grading. Among the mitral morphologic parameters, the mitral annular (MA) dimension index and the hamstringing phenomenon of the posterior mitral leaflet were independent determinants of MR grading. Significant MR was not seen in patients without LA dilatations, but it occurred in 14% of patients with LA dilatation alone and in 55% with both LA and LV dilatations; the MA dimension index increased in this order.Conclusions:The grading of functional MR occurring in patients with AF and preserved LVEF depends on both the LA dimension and the LV systolic dimension. The MR grading also depends on both the MA dilatation and the hamstringing phenomenon of the posterior mitral leaflet.
机译：背景：尽管保存的左心室喷射部分（LVEF），心房颤动（AF）患者左心房（LA）扩张可以诱导功能二尖瓣反流（MR）。本研究的目的是探讨该功能Mr.Methods的病因：我们回顾性地检查了5,202个连续案例的临床和超声心动图数据，该数据在经过触发超声心动图的连续案例中。 AF出现在544名患者中，除了患有其他潜在的心脏病患者之后，我们选择159例159次，= 50％。结果：13名（8.2％）患者中，官能先生的职能MR显着（中等或更大）。患者患者患者持续时间> 10年比其他患者（27 vs.4％，p = 0.0057）。多元回归分析表明，La尺寸指数和左心室（LV）收缩尺寸指数是MR分级的独立决定因素。二尖瓣形态学参数中，二尖瓣环（MA）尺寸指数和后二尖瓣叶的腿筋现象是MR分级的独立决定因素。没有La扩张的患者没有见到重要的MR，但它以14％的患者发生在La和LV扩张中的14％的La扩张患者中; MA尺寸指数按此顺序增加。链接：AF和保存的LVEF患者中发生的功能MR的分级取决于LA尺寸和LV收缩尺寸。 SR分级也取决于MA扩张和后部宣传叶的腿筋现象。

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