Molecular imaging and theranostic approaches in pheochromocytoma and paraganglioma

David Ta?eb; Karel Pacak

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Molecular imaging and theranostic approaches in pheochromocytoma and paraganglioma

机译：嗜铬细胞瘤和伞形脑瘤的分子成像和治疗方法

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Pheochromocytomas and their extra-adrenal counterpart paragangliomas (PGLs; together called PPGLs), belong to the family of neural crest-derived tumors. Given the overexpression of a wide variety of specific targets in PPGLs, it seems that these tumors are optimally suited to be imaged by specific radiopharmaceuticals. Thus, theranostics approaches with somatostatin agonists and antagonists are rapidly evolving in the setting of these tumors and may be considered as the next step in the therapeutic arsenal of metastatic PPGLs.

机译：Pheochromytomas及其额外的肾上腺对手Paragangliomas（PGLS;一起称为PPGLS），属于神经嵴衍生的肿瘤系列。鉴于PPGLS中各种特定靶标的过表达，似乎这些肿瘤最佳地由特定放射性药物成像。因此，具有生长抑素激动剂和拮抗剂的治疗方法在这些肿瘤的设置中迅速发展，并且可以被认为是转移性PPG1的治疗库中的下一步骤。

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来源
《Cell and Tissue Research》 |2018年第2期|共9页
作者
David Ta?eb; Karel Pacak;
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作者单位

Department of Nuclear Medicine La Timone University Hospital CERIMED Aix-Marseille University;

Section on Medical Neuroendocrinology Eunice Kennedy Shriver National Institute of Child Health;

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原文格式 PDF
正文语种 eng
中图分类细胞生物学;
关键词
Positron emission tomography; Gallium-68; DOTA-analogues; 6-(18F)fluoro-L-3; 4-dihydroxyphenylalanine; Somatostatin; Paragangliomas; Neuroendocrine;

机译：正电子发射断层扫描;镓-68;dota-类似物;6-（18°F）氟-1-3;4-二羟基苯基丙氨酸;生长抑制素;Paragangliomas;神经内分泌;

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专利

1. Molecular imaging and theranostic approaches in pheochromocytoma and paraganglioma [J] . David Ta?eb, Karel Pacak Cell and Tissue Research . 2018,第2期

机译：嗜铬细胞瘤和伞形脑瘤的分子成像和治疗方法
2. Imaging of pheochromocytoma and paraganglioma: moving beyond “lumpology” with SSTR, FDG and MIBG molecular imaging [J] . D Pattison, RJ Hicks Cancer Imaging . 2015,第1期

机译：嗜铬细胞瘤和副神经节瘤的成像：通过SSTR，FDG和MIBG分子成像超越“肿块学”
3. Imaging of pheochromocytoma and paraganglioma: moving beyond “lumpology” with SSTR, FDG and MIBG molecular imaging [J] . D Pattison, RJ Hicks Cancer Imaging . 2015,第1期

机译：嗜铬细胞瘤和副神经节瘤的成像：通过SSTR，FDG和MIBG分子成像超越“肿块学”
4. H_2O_2-Activatable Contrast-Enhanced Photoacoustic Imaging and Antithrombotic Therapy using Molecularly Engineered Theranostic Nanoparticles [C] . Dongwon Lee, Eunkyeong Jung, Changsun Rang, Society for Biomaterials annual meeting and exposition . 2018

机译：H_2O_2可激活的对比度增强光声成像和抗血栓治疗的分子工程化治疗纳米颗粒。
5. PET Theranostics for Molecular Imaging and Radioimmunotherapy of Pancreatic Cancer [D] . Boyle, Amanda Jean. 2019

机译：胰腺癌分子影像学和放射免疫疗法的PET治疗学
6. Current and Future Anatomical and Functional Imaging Approaches to Pheochromocytoma and Paraganglioma [O] . H. J. L. M. Timmers, D. Taieb, K. Pacak -1

机译：嗜铬细胞瘤和伞菌性瘤和神经植物瘤的当前和未来的解剖和功能成像方法
7. Current and Future Anatomical and Functional Imaging Approaches to Pheochromocytoma and Paraganglioma [O] . H.J.L. Timmers, D. Taieb, K. Pacak 2012

机译：嗜铬细胞瘤和伞菌性瘤和神经植物瘤的当前和未来的解剖和功能成像方法

Molecular imaging and theranostic approaches in pheochromocytoma and paraganglioma

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