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Nucleotide-independent cytoskeletal scaffolds in bacteria

机译：细菌中不依赖核苷酸的细胞骨架支架

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摘要

Bacteria possess a diverse set of cytoskeletal proteins that mediate key cellular processes such as morphogenesis, cell division, DNA segregation, and motility. Similar to eukaryotic actin or tubulin, many of them require nucleotide binding and hydrolysis for proper polymerization and function. However, there is also a growing number of bacterial cytoskeletal elements that assemble in a nucleotide-independent manner, including intermediate filament-like structures as well several classes of bacteria-specific polymers. The members of this group form stable scaffolds that have architectural roles or act as localization factors recruiting other proteins to distinct positions within the cell. Here, we highlight the elements that constitute the nucleotide-independent cytoskeleton of bacteria and discuss their biological functions in different species.
机译：细菌拥有多种多样的细胞骨架蛋白，它们介导关键的细胞过程，例如形态发生，细胞分裂，DNA分离和运动。与真核肌动蛋白或微管蛋白相似，它们中的许多都需要核苷酸结合和水解才能正常聚合和发挥作用。然而，越来越多的细菌细胞骨架元件以核苷酸非依赖性方式组装，包括中间的丝状结构以及几类细菌特异性聚合物。该组成员形成稳定的支架，这些支架具有结构性作用或充当将其他蛋白质募集到细胞内不同位置的定位因子。在这里，我们重点介绍了构成细菌的核苷酸非依赖性细胞骨架的元素，并讨论了它们在不同物种中的生物学功能。

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