LncRNA-XIST promotes dermal papilla induced hair follicle regeneration by targeting miR-424 to activate hedgehog signaling

Lin Bo-Jie; Zhu Jiang-Ying; Ye Jun; Lu Si-Ding; Liao Ming-De; Meng Xu-Chang; Yin Guo-Qian

首页> 外文期刊>Cellular Signalling >LncRNA-XIST promotes dermal papilla induced hair follicle regeneration by targeting miR-424 to activate hedgehog signaling

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LncRNA-XIST promotes dermal papilla induced hair follicle regeneration by targeting miR-424 to activate hedgehog signaling

机译：LNCRNA-XIST通过靶向miR-424来激活刺猬信号传导，促进皮肤乳头诱导的毛囊再生

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Background: Alopecia is a highly prevalent disease characterizing by the loss of hair. Dermal papilla (DP) cells are the inducer of hair follicle regeneration, and in vitro three-dimensional (3D) culturing DP cells have been proven to induce hair follicle regeneration. However, the molecular mechanisms behind the regulation of 3D culturing DP cells remain unclear.

机译：背景：Alopecia是一种高度普遍的疾病，表征了头发的丧失。皮脂乳头（DP）细胞是毛囊再生的诱导剂，并且已经证明培养DP细胞的体外三维（3D）以诱导毛囊再生。然而，3D培养DP细胞调节背后的分子机制仍然不清楚。

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来源
《Cellular Signalling》 |2020年第2020期|共10页
作者
Lin Bo-Jie; Zhu Jiang-Ying; Ye Jun; Lu Si-Ding; Liao Ming-De; Meng Xu-Chang; Yin Guo-Qian;
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作者单位

Guangxi Med Univ Dept Plast &

Aesthet Surg Affiliated Hosp 1 6 Shuangyong Rd Nanning 530021 Guangxi Provinc Peoples R China;

Guangxi Med Univ Acad Humanities &

Social Sci Nanning 530021 Guangxi Provinc Peoples R China;

Xiangya Med Coll CSU Dept Emergency Surg Affiliated Zhuzhou Hosp Zhuzhou 412007 Hunan Peoples R China;

Guangxi Med Univ Dept Plast &

Aesthet Surg Affiliated Hosp 1 6 Shuangyong Rd Nanning 530021 Guangxi Provinc Peoples R China;

Guangxi Med Univ Dept Plast &

Aesthet Surg Affiliated Hosp 1 6 Shuangyong Rd Nanning 530021 Guangxi Provinc Peoples R China;

Guangxi Med Univ Dept Plast &

Aesthet Surg Affiliated Hosp 1 6 Shuangyong Rd Nanning 530021 Guangxi Provinc Peoples R China;

Guangxi Med Univ Dept Plast &

Aesthet Surg Affiliated Hosp 1 6 Shuangyong Rd Nanning 530021 Guangxi Provinc Peoples R China;

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原文格式 PDF
正文语种 eng
中图分类细胞形态学;
关键词
lncRNA-XIST; miR-424; Hedgehog signaling pathway; Dermal papilla; Hair follicle regeneration;

机译：lncran-xist;mir-424;刺猬信号通路;皮肤乳头;毛囊再生;

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专利

1. LncRNA-XIST promotes dermal papilla induced hair follicle regeneration by targeting miR-424 to activate hedgehog signaling [J] . Lin Bo-Jie, Zhu Jiang-Ying, Ye Jun, Cellular Signalling . 2020,第期

机译：LNCRNA-XIST通过靶向miR-424来激活刺猬信号传导，促进皮肤乳头诱导的毛囊再生
2. 3-Deoxysappanchalcone Promotes Proliferation of Human Hair Follicle Dermal Papilla Cells and Hair Growth in C57BL/6 Mice by Modulating WNT/beta-Catenin and STAT Signaling [J] . Kim Young Eun, Choi Hyung Chul, Lee In-Chul, Biomolecules & therapeutics . 2016,第6期

机译：3-Deoxysappanchalcone通过调节WNT /β-Catenin和STAT信号传导促进人毛囊真皮乳头细胞的增殖和C57BL / 6小鼠的头发生长
3. Identification of transcriptional targets of Wnt/beta-catenin signaling in dermal papilla cells of human scalp hair follicles: EP2 is a novel transcriptional target of Wnt3a. [J] . Shin H, Kwack MH, Shin SH, Journal of dermatological science . 2010,第2期

机译：鉴定人头皮毛囊的真皮乳头细胞中Wnt /β-catenin信号转导的转录靶标：EP2是Wnt3a的新型转录靶标。
4. Interactions of Dermal Papilla Spheroid Array and Acellular Skin Dermis during Hair Follicle Regeneration [C] . Yi-You Huang, Chia-Hsiem Tsai Society for Biomaterials annual meeting and exposition . 2019

机译：毛囊再生过程中真皮乳头球状体阵列与脱细胞皮肤真皮的相互作用
5. Missing in metastasis is a basal body-associated protein that regulates ciliogenesis, sonic hedgehog signaling and hair follicle regeneration. [D] . Bershteyn, Marina. 2009

机译：转移中缺少的是一种基础身体相关蛋白，它调节纤毛形成，声波刺猬信号和毛囊再生。
6. LncRNA H19 Overexpression Activates Wnt Signaling to Maintain the Hair Follicle Regeneration Potential of Dermal Papilla Cells [O] . Ningxia Zhu, En Lin, Huan Zhang, 2020

机译：LNCRNA H19过表达激活WNT信号以保持皮脂乳头细胞的毛囊再生电位
7. LncRNA H19 Overexpression Activates Wnt Signaling to Maintain the Hair Follicle Regeneration Potential of Dermal Papilla Cells [O] . Ningxia Zhu, En Lin, Huan Zhang, 2020

机译：LNCRNA H19过表达激活WNT信号，以保持皮脂乳头细胞的毛囊再生电位

LncRNA-XIST promotes dermal papilla induced hair follicle regeneration by targeting miR-424 to activate hedgehog signaling

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