...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Chaos, Solitons and Fractals: Applications in Science and Engineering: An Interdisciplinary Journal of Nonlinear Science >Multifractal analysis of embryonic eye structures from female mice with dietary folic acid deficiency. Part I: Fractal dimension, lacunarity, divergence, and multifractal spectrum
【24h】

Multifractal analysis of embryonic eye structures from female mice with dietary folic acid deficiency. Part I: Fractal dimension, lacunarity, divergence, and multifractal spectrum

机译：膳食叶酸缺乏雌性小鼠胚胎眼结构的多重分析。 第一部分：分形尺寸，姿势，分歧和多重分谱

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

The purpose of this study was to investigate effects of low maternal folic acid (FA) status on many eye structures in embryonic mice using multifractal analysis, a method for describing complex structural patterns. To do this, we used the FracLac plugin for ImageJ to analyse binary digital images of cornea, lens, retina, and vitreous after immunohistochemical analysis using anti-collagen IV or anti-laminin-1 antibodies. The box-counting and gliding box methods were used to generate metrics including the fractal dimension, lacunarity, divergence, and multifractal spectrum distance metrics for each ocular structure. Results were analysed using bootstrap resampling techniques and the Kruskal-Wallis significance test. For all structures and staining methods studied, differences between embryos from control vs FA-deficient females were detectable in lacunarity plots and multifractal spectra, and statistically significant in cornea, lens, retina and vitreous. Multifractal analysis detected even slight differences in tissue textures presumably attributable to altered expression of extracellular matrix molecules. (c) 2020 Elsevier Ltd. All rights reserved.
机译：本研究的目的是研究使用多法分析的胚胎小鼠在胚胎小鼠中的许多眼部结构的影响，这是一种描述复杂结构图案的方法。为此，我们使用了使用抗胶原IV或抗层状蛋白-1抗体在免疫组化分析后分析了Imagej的Fraclac插件来分析角膜，镜片，视网膜和玻璃体的二元数字图像。盒子计数和滑动盒方法用于产生每个眼部结构的分形尺寸，姿势，发散和多重谱距离度量的度量。使用自动启动重采样技术和Kruskal-Wallis意义测试分析了结果。对于所研究的所有结构和染色方法，可检测来自对照VS FA缺陷的女性的胚胎之间的差异，在角膜内的曲线图和多重谱中，在角膜，镜片，视网膜和玻璃体中有统计学意义。多法分析检测到甚至可能是由于改变细胞外基质分子的表达的组织纹理的细微差异。 （c）2020 elestvier有限公司保留所有权利。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号