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Two-Step Directional Surface Modification of Iron Oxide Nanoparticles with Protected Siloxanes

机译:用保护硅氧烷的氧化铁纳米粒子的两步定向表面改性

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摘要

Successful surface modification of iron oxide nanoparticles is crucial for their usage in applications. However, ligand exchange methods introducing siloxanes have several drawbacks. Presented here is a novel approach for the surface modification of iron oxide nanoparticles by making use of siloxanes, synthesized by thiol-ene click chemistry, with protected functional groups. Afterwards the ligands are deprotected to liberate their functionality. This approach solves the issues related to ligand orientation and colloidal stability during surface modification.
机译:氧化铁纳米颗粒的成功表面改性对于它们在应用中的使用至关重要。 然而,引入硅氧烷的配体交换方法具有几个缺点。 此处提出是通过使用硅氧烷的氧化氧化铁纳米粒子的表面改性的新方法,用硫醇-NE键合并化学,用保护的官能团。 之后,将配体脱保护以释放它们的功能。 该方法解决了表面改性期间与配体取向和胶体稳定性相关的问题。

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