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首页> 外文期刊>Clinical EEG and neuroscience: official journal of the EEG and Clinical Neuroscience Society (ENCS) >Electroencephalography Findings in Crohn's Disease
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Electroencephalography Findings in Crohn's Disease

机译：克罗恩病中的脑电图结果

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摘要

Objectives. Crohn's Disease (CD) is a chronic systemic inflammatory disease associated with various extraintestinal manifestations, including seizure as a neurological finding. In this study, the prevalence of seizure and electroencephalographic abnormalities in patients with CD was investigated. Materials and Methods. This study involved 41 patients with CD (female/male: 25/16) and 39 subjects in the control group (female/male: 25/14). Patients in the CD group were diagnosed and monitored according to the European Crohn's and Colitis Organization diagnostic criteria. The control group was composed of healthy subjects with similar age and sex as the CD group. Seizures were classified according to the criteria of the International League Against Epilepsy. Electroencephalography (EEG) was performed for all patients with CD and for healthy subjects. Seizure prevalence and EEG findings were also compared. Results. One patient in the CD group had history of seizures. EEG abnormality was significantly higher in the CD group (16/41, 39%) (P = .001). The most common EEG abnormality was intermittent generalized slow wave abnormality in theta frequency. Discussion. Our study indicated that CD was associated with EEG abnormalities rather than seizure. The results also indicated that EEG was a potential indicator for detecting subclinical neurological abnormalities in CD.
机译：目标。克罗恩病（CD）是一种与各种肾外表现相关的慢性全身性炎症疾病，包括癫痫发作作为神经系统发现。在该研究中，研究了CD患者癫痫发作和脑电图异常的患病率。材料和方法。本研究涉及41例CD（女性/男性：25/16）和对照组的39名受试者（女性/男性：25/14）。根据欧洲克罗恩和结肠炎组织诊断标准，诊断和监测CD组中的患者。对照组由健康受试者组成，具有类似年龄和性别作为CD组。缉获量根据国际联盟对抗癫痫的标准进行分类。对所有CD和健康受试者进行脑电图（EEG）。还比较了癫痫发育和EEG结果。结果。 CD组中的一名患者有癫痫发作的历史。 CD组（16/41,39％）（P = .001）脑电图异常显着高。最常见的EEG异常是θ频率间歇的广义慢波异常。讨论。我们的研究表明，CD与脑电图异常而非癫痫发作相关。结果还表明，EEG是用于检测CD中亚临床神经学异常的潜在指标。

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