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Evaluation of Neurofeedback for Posttraumatic Stress Disorder Related to Refugee Experiences Using Self-Report and Cognitive ERP Measures

机译:利用自我报告和认知ERP措施评估与难民经验相关的难治性应激障碍的神经融合

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Background. Neurofeedback holds promise as an intervention for the psychophysiological dysfunction found in posttraumatic stress disorder (PTSD). Few empirical studies have assessed the efficacy of neurofeedback for PTSD, and none in individuals with refugee trauma. A proposed mechanism for neurofeedback efficacy in PTSD is through remediating deficits in cognitive control. We assessed pre- and postchanges in symptoms and neurocognitive functioning of refugee clients participating in a neurofeedback intervention for PTSD. Methods. Clinical data for 13 adult refugees with chronic PTSD who participated in neurofeedback combined with trauma counseling (NFT) was compared with 13 adult refugees placed on a waitlist to receive neurofeedback. Waitlist clients continued to receive trauma counseling alone (TC). NFT was additionally assessed pre- and posttherapy for changes in event-related potentials (ERPs) and behavioral indices of cognitive control using a visual continuous performance task (VCPT). Comparison VCPT data from healthy controls (HC) was available from the Human Brain Index database. Results. Posttherapy, NFT had significantly lower symptoms of trauma, anxiety, and depression compared with TC. NFT demonstrated an increased P3 amplitude and improved behavioral performance suggesting a normalization of cognitive control. Conclusions. These preliminary observations are consistent with a possible benefit of neurofeedback for remediating PTSD. This may be achieved at least partially by an improvement in cognitive control. Further confirmation of the effectiveness of the treatment now requires a randomized controlled trial that considers issues such as placebo response, nonspecific therapist effects, and duration of treatment.
机译:背景。 Neurofeedback认为承诺作为在创伤性应激障碍(PTSD)中发现的心理生理功能障碍的干预。少数实证研究已经评估了神经融合对应激障碍的疗效,没有难民创伤的个体。 PTSD中神经融合疗效的提出机制是通过修复认知控制中的缺陷。我们评估了难民客户参与PTSD的神经融合干预的难民客户的症状和神经认知功能。方法。将参与Neurofeedback的慢性PTSD的13名成人难民与创伤咨询(NFT)相结合的临床资料与13名成人难民放在候补名单上,以获得神经融合。候补客户端继续接受单独创伤咨询(TC)。另外,使用可视连续性能任务(VCPT),另外评估了与事件相关潜力(ERP)和认知控制行为指标的改变的预后治疗。比较来自人类脑索引数据库的健康控制(HC)的VCPT数据。结果。后疗法,与TC相比,NFT显着降低了创伤,焦虑和抑郁症的症状。 NFT展示了增加的P3幅度和改善的行为性能,表明认知控制的标准化。结论。这些初步观察结果与神经融合的可能益处一致,用于修复重新提出应激障碍。这可以至少部分地通过改善认知控制来实现。进一步确认治疗的有效性现在需要一种随机对照试验,该试验考虑安慰剂反应,非特异性治疗师效应和治疗持续时间。

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