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首页> 外文期刊>Clinical neuropharmacology >Topiramate-associated urinary incontinence: A case verified by rechallenge
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Topiramate-associated urinary incontinence: A case verified by rechallenge

机译：Topiramate相关的尿失禁：通过重新检查验证的案例

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摘要

Topiramate is an anticonvulsant that has been widely used in psychiatric conditions. Themost common treatment-related adverse effects of topiramate were diarrhea, nausea, loss of appetite, fatigue, paresthesia, cognitive impairment, and metabolic acidosis. The following is a case report intended to draw attention to a rarely reported adverse effect of topiramate. A male patient treated with topiramate developed urinary incontinence that was considered drug associated because of the temporal relationship between its appearance and the commencement of topiramate, its resolution upon topiramate discontinuation, and its recurrence with topiramate rechallenge. Urinary incontinence, although not life threatening, can be a distressing problem with a profound impact on quality of life. This case reminds that physicians prescribing topiramate should be aware of this possible adverse effect and communicate it to patients and their caregivers.
机译：Topiramate是一种抗惊厥药，已被广泛用于精神病疾病。 拓扑普通治疗有关的托吡酯的不良反应是腹泻，恶心，食欲不振，疲劳，感觉，认知障碍和代谢酸中毒。 以下是案例报告，旨在提请注意拓扑酸酯的很少报告的不良影响。 用拓扑酸酯治疗的男性患者产生了尿失禁，被认为是由于其外观与托吡酯的出现之间的时间关系而相关的药物，其在秋三酸盐停止时的分辨率，及其与托吡酯重组的复发。 尿失禁，虽然没有生命威胁，可能是对生活质量影响的令人痛苦的问题。 本案提醒那个处方的医生应意识到这种可能的不利影响，并将其与病人及其护理人员传达。

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  • 来源
    《Clinical neuropharmacology》 |2014年第5期|共2页
  • 作者

    WangC.-F.; HoP.-S.; TsengY.-T.; LiangC.-S.;

  • 作者单位

    Department of Psychiatry Beitou Branch Tri-Service General Hospital No 60 Xinmin RdBeitou;

    Department of Psychiatry Beitou Branch Tri-Service General Hospital No 60 Xinmin RdBeitou;

    Department of Psychiatry Beitou Branch Tri-Service General Hospital No 60 Xinmin RdBeitou;

    Department of Psychiatry Beitou Branch Tri-Service General Hospital No 60 Xinmin RdBeitou;

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  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 药理学;
  • 关键词

    Case report; Rechallenge; Topiramate; Urinary incontinence;

    机译：案例报告;重新开始;Topiramate;尿失禁;

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