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首页> 外文期刊>Comparative Medicine >Sequelae of Occult Aggression Disqualifying Young, Socially Housed, Female New Zealand White Rabbits (Oryctolagus cuniculus) from Participation in Dermal Toxicology Studies
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Sequelae of Occult Aggression Disqualifying Young, Socially Housed, Female New Zealand White Rabbits (Oryctolagus cuniculus) from Participation in Dermal Toxicology Studies

机译：隐匿性侵略性的后遗症取消了年轻，社会居住，女性新西兰白兔（Oryctolagus cuniculus）免于参与皮肤毒理学研究

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International animal welfare organizations and federal, regional, and institutional oversight bodies encourage social housing of gregarious species, such as New Zealand white rabbits (Oryctolagus cuniculus), to promote animal wellbeing in research, teaching, testing and farming settings. At our institution, 2 groups of female New Zealand white rabbits (approximate age, 11 wk; mean weight, 2.35 kg), compatibly paired at the vendor for 5 wk, were paired in caging or group-housed in a floor pen. The rabbits appeared compatible, demonstrating primarily affiliative behaviors throughout 6 wk of daily observations. However, occult aggression that occurred between daily observations or nocturnally resulted in skin wounding. The skin injuries, first identified during prestudy clipping of fur from the back of each rabbit 6 wk after arrival, disqualified every animal from participation in skin toxicology and muscle implantation studies. Success meeting scientific research requirements while promoting animal welfare and health when socially housing New Zealand white rabbits requires examining the behavioral repertoire of their wild counterparts, European rabbits. Factors including age, sex, and housing density influence territoriality, dominance hierarchy, social ranking, and natural, agonistic, injurious, behavioral tendencies. IACUC and other relevant oversight bodies, researchers, and animal care staff should consider this case study and the species-specific natural history of New Zealand white rabbits when assessing the harm and benefit of social housing in regard to research utility and animal welfare.
机译：国际动物福利组织和联邦，区域和机构监督机构鼓励血腥物种的社会住房，如新西兰白兔（Oryctolagus cuniculus），以促进在研究，教学，测试和农业环境中的动物福祉。在我们的机构，2组女性新西兰白兔（近似年龄，11周;平均重量，2.35千克）在供应商处搭配5个WK，在船舶笔中配对或群组合。兔子出现兼容，展示了在6周的每日观察中的主要行为。然而，日常观察或夜间发生的神秘攻击导致皮肤伤害。皮肤损伤，首先在到达后从每只兔子6周后的毛皮剪裁，取消了从参与皮肤毒理学和肌肉植入研究的情况下取消资格。在社会住房新西兰白兔时促进动物福利和健康的同时，促进动物福利和健康的成功需要检查欧洲兔的行为曲目。包括年龄，性别和住房密度的因素会影响地区，主导层次，社会排名和自然，激动，有害，行为趋势。 IACUC和其他相关监督机构，研究人员和动物护理人员应考虑这种情况研究和新西兰白兔的物种特异性自然历史，在评估社会住房关于研究效用和动物福利的危害和好处。

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