MiR-182 enhances radioresistance in non-small cell lung cancer cells by regulating FOXO3

Gang Chen; Lina Yu; Hui Dong; ?Zhihao Liu; ?Yahong Sun

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MiR-182 enhances radioresistance in non-small cell lung cancer cells by regulating FOXO3

机译：MiR-182通过调节FoxO3增强非小细胞肺癌细胞的辐射敏感度

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Upregulated in lung cancer, miRNA-182 was found to be related to cancer proliferation and chemoresistance. However, there is no report on the role of miR-182 in radioresistance, which is a main obstacle of radiotherapy. In this study, we aim to depict the effect of miR-182 inhibition on cellular sensitivity to ionizing radiation. Our data confirm that miR-182 is upregulated in lung cancers and tissues and that miR-182 is

机译：发现MiRNA-182在肺癌中升级与癌症增殖和化学性有关。然而，没有关于MIR-182在放射侵蚀性中的作用的报告，这是放射治疗的主要障碍。在这项研究中，我们的目标是描述miR-182抑制对电离辐射细胞敏感性的影响。我们的数据确认miR-182在肺癌和组织中上调，mir-182是

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《Clinical and experimental pharmacology & physiology》 |2019年第2期|共7页
作者
Gang Chen; Lina Yu; Hui Dong; ?Zhihao Liu; ?Yahong Sun;
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Department of Respiratory Medicine People’s Hospital of Haining Haining China;

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正文语种 eng
中图分类药理学;
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1. MiR-182 enhances radioresistance in non-small cell lung cancer cells by regulating FOXO3 [J] . Gang Chen, Lina Yu, Hui Dong, Clinical and experimental pharmacology & physiology . 2019,第2期

机译：MiR-182通过调节FoxO3增强非小细胞肺癌细胞的辐射敏感度
2. Autophagy enhanced the radioresistance of non-small cell lung cancer by regulating ROS level under hypoxia condition [J] . Chen Xiaoyan, Wang Ping, Guo Fei, International Journal of Radiation Biology: Covering the Physical, Chemical, Biological, and Medical Effects of Ionizing and Non-ionizing Radiations . 2017,第8期

机译：通过根据缺氧条件调节ROS水平，自噬增强了非小细胞肺癌的辐射敏感度
3. Knockdown of TC-1 enhances radiosensitivity of non-small cell lung cancer via the Wnt/???2-catenin pathway Knockdown of TC-1 enhances radiosensitivity of non-small cell lung cancer via the Wnt/???2-catenin pathway Knockdown of TC-1 enhances radiosensitivity of non-small cell lung cancer via the Wnt/???2-catenin pathway [J] . Dapeng Wu, Wei Yan, Lei Li Biology Open . 2016,第4期

机译：TC-1的抑制通过Wnt /β2-catenin途径增强非小细胞肺癌的放射敏感性TC-1的抑制通过Wnt /β2-catenin途径增强非小细胞肺癌的放射敏感性TC-1的抑制通过Wnt /β2-catenin途径增强非小细胞肺癌的放射敏感性
4. Enumeration and ALK Investigation of Circulating Tumor Cells in Non-Small Cell Lung Cancer (NSCLC) Patients Using an Effective In Vivo Technology, the GILUPI CellCollector? [C] . Klaus Luecke, Lukasz Gasiorowski, Stefanie Herold, International Molecular Medicine Tri-Conference. . 2015

机译：使用有效的体内技术（Gilupi Cellcollector
5. Stromal Lysyl Oxidase-Like 1 Increases Extracellular Matrix Stiffness and Enhances Collagen Fibre Alignment in Non-Small Cell Lung Cancer. [D] . Pasko, Elena. 2015

机译：基质赖氨酸氧化酶样1在非小细胞肺癌中可增加细胞外基质的刚度并增强胶原纤维的排列。
6. Calcium channel α2δ1 subunit (CACNA2D1) enhances radioresistance in cancer stem-like cells in non-small cell lung cancer cell lines [O] . Xin Sui, Jian-Hao Geng, Yong-Heng Li, 2018

机译：钙通道α2δ1亚基（CACNA2D1）增强非小细胞肺癌细胞系中癌干样细胞的抗辐射能力
7. Plasminogen activator inhibitor-1 enhances radioresistance and aggressiveness of non-small cell lung cancer cells [O] . JiHoon Kang, Wanyeon Kim, TaeWoo Kwon, 2016

机译：纤溶酶原激活剂抑制剂-1增强了非小细胞肺癌细胞的辐射敏感度和侵袭性

MiR-182 enhances radioresistance in non-small cell lung cancer cells by regulating FOXO3

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