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93 Practical Outpatient Pharmacotherapy for Alcohol Use Disorder

机译:93用于酒精使用障碍的实用门诊药物疗法

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Alcohol use disorder (AUD) is commonly encountered in clinical practice. A combination of psychosocial intervention and pharmacotherapy is the cornerstone of AUD treatment. Despite their efficacy, safety and cost-effectiveness, clinicians are reluctant to prescribe medications to treat individuals with AUD. Given the high rate of relapse with psychosocial intervention alone, increasing patient access to this underutilized treatment has the potential to improve clinical outcome in this difficult-to-treat population. Herein, we provide practical pharmacotherapy strategies to improve treatment outcome for AUD. We review the efficacy and side effects of both on- and off-label agents with a particular focus on clinical applicability. Recommendations are supported by findings from randomized controlled trials (RCT) and meta-analyses selected to be representative, where possible, of current treatment guidelines. The goal of this paper is to help readers use pharmacotherapy with greater confidence when treating patients with AUD.
机译:临床实践中通常遇到酒精使用障碍(AUD)。心理社会干预和药物疗法的组合是AUD治疗的基石。尽管他们有效,安全性和成本效益,临床医生不愿意开出药物以治疗个人患者。仅鉴于单独的心理社会干预率高,患者对这种未充分利用的治疗的进入增加有可能改善这种难以治疗的人群的临床结果。在此,我们提供实际的药物疗法策略,以改善澳元的治疗结果。我们审查了与临床适用性特别关注的开启和非标签代理的疗效和副作用。随机对照试验(RCT)的调查结果支持建议,并在可能的情况下选择代表的荟萃分析,在可能的情况下,可能是当前的治疗准则。本文的目标是帮助读者在治疗患者患者时使用药物治疗。

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