Mechanism of action of vesicular monoamine transporter 2 (VMAT2) inhibitors in tardive dyskinesia: reducing dopamine leads to less “go” and more “stop” from the motor striatum for robust therapeutic effects

Stephen M.Stahl

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Mechanism of action of vesicular monoamine transporter 2 (VMAT2) inhibitors in tardive dyskinesia: reducing dopamine leads to less “go” and more “stop” from the motor striatum for robust therapeutic effects

机译：腐败的止吐管瘤中的凹凸单胺转运蛋白2（VMAT2）抑制剂的作用机制：减少多巴胺导致从电机纹状体的较低“去”，更“止挡”，以稳健的治疗效果

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Tardive dyskinesia can now be successfully treated by inhibiting the vesicular monoamine transporter type 2 (VMAT2).

机译：现在可以通过抑制囊泡单胺转运蛋白2（VMAT2）来成功治疗Tardive Dyskinesia。

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《CNS spectrums》 |2018年第1期|共6页
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Stephen M.Stahl;
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中图分类神经病学与精神病学;
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1. Mechanism of action of vesicular monoamine transporter 2 (VMAT2) inhibitors in tardive dyskinesia: reducing dopamine leads to less “go” and more “stop” from the motor striatum for robust therapeutic effects [J] . Stephen M.Stahl CNS spectrums . 2018,第1期

机译：腐败的止吐管瘤中的凹凸单胺转运蛋白2（VMAT2）抑制剂的作用机制：减少多巴胺导致从电机纹状体的较低“去”，更“止挡”，以稳健的治疗效果
2. Tardive dyskinesia: placing vesicular monoamine transporter type 2 (VMAT2) inhibitors into clinical perspective [J] . Citrome, L. Expert review of neurotherapeutics . 2018,第1a6期

机译：Tardive Dyskinesia：将凹凸单胺转运蛋白2（VMAT2）抑制剂放入临床视角
3. Genetic deletion of vesicular monoamine transporter-2 (VMAT2) reduces dopamine transporter activity in mesencephalic neurons in primary culture. [J] . Yamamoto H, Kamegaya E, Hagino Y, Neurochemistry International: The International Journal for the Rapid Publication of Critical Reviews, Preliminary and Original Research Communications in Neurochemistry . 2007,第2a4期

机译：囊泡单胺转运蛋白2（VMAT2）的基因删除降低了原代培养中脑神经元的多巴胺转运蛋白活性。
4. Design, synthesis, and pharmacological evaluation of three series of lobelane analogs as inhibitors of the vesicular monoamine transporter (VMAT2). [D] . Culver, John P. 2015

机译：设计，合成和药理学评估三个系列的环氧丙烷类似物作为水泡单胺转运蛋白（VMAT2）的抑制剂。
5. Dopamine D1 D2 D3 Receptors Vesicular Monoamine Transporter Type-2 (VMAT2) and Dopamine Transporter (DAT) Densities in Aged Human Brain [O] . Jianjun Sun, Jinbin Xu, Nigel J. Cairns, -1

机译：多巴胺D1D2D3受体囊泡单胺转运类型2（VmaT2）和多巴胺转运蛋白（DaT）密度在老年人脑
6. Dopamine D1, D2, D3 receptors, vesicular monoamine transporter type-2 (VMAT2) and dopamine transporter (DAT) densities in aged human brain. [O] . Jianjun Sun, Jinbin Xu, Nigel J Cairns, 2012

机译：多巴胺D1，D2，D3受体，囊泡单胺转运蛋白2型（VmaT2）和多巴胺转运蛋白（DaT）在老年人脑中的密度。

Mechanism of action of vesicular monoamine transporter 2 (VMAT2) inhibitors in tardive dyskinesia: reducing dopamine leads to less “go” and more “stop” from the motor striatum for robust therapeutic effects

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