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Fragrant and sticky allergens from the pinewood: Cohabiting and coreacting

机译:来自Pinewood的香味和粘性过敏原:同居和核酸

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SUMMARY Background Tree moss ( Pseudevernia furfuracea [L.] Zopf.), a lichen growing on conifers, is a frequent fragrance sensitizer. Previous studies have shown two subgroups of tree moss‐allergic patients: a group sensitized to common allergens of tree and oak moss ( Evernia prunastri ), and another group sensitized to colophonium‐derived allergens, which may contaminate tree moss extract. Objectives To report the results of including tree moss extract in the baseline series and discuss the clinical implications. Methods Tree moss extract was included in the baseline series and sensitized patients were assessed for concomitant allergy to colophonium and oak moss, and the relevance of these reactions was analyzed. Results Altogether, 22 of 632 patients (3.5%) had positive reactions to tree moss. Eight patients were sensitized to tree moss only (among fragrance allergens) and 75% had relevant reactions to colophonium. Fourteen patients were sensitized to other fragrance allergens as well and 28.5% had relevant colophonium reactions. Conclusions The prevalence of positive tree moss reactions is high enough to justify its inclusion in the baseline series. If tree moss is not included, patients with positive colophonium reactions should be informed of possible (false) cross‐reactivity to tree moss to avoid this labeled fragrance allergen.
机译:摘要背景树苔藓(假霉素糠醛[L.] Zopf。),一种在针叶树上生长的地衣是一种常心的香味敏化剂。以往的研究显示了树膜过敏患者的两组亚组:一群致力于树木和橡树藓(Evernia Prunastri)的常见过敏原,以及另一个致力于肠系衍生过敏原的群体,这可能污染树苔藓提取物。目的在基线系列中报告包括树苔原提取物的结果,并讨论临床意义。方法采用树木苔藓提取物中包含基线系列和敏化患者,评估对肠系和橡树苔的伴随过敏,分析了这些反应的相关性。结果,632名患者中的22例(3.5%)对树苔有阳性反应。八名患者敏感到树苔(香料过敏原),75%对肠系中有相关的反应。 4名患者也敏感到其他香味过敏原,28.5%具有相关的肠球反应。结论阳性树木苔反应的普遍性足以使其在基线系列中的包容性致力于。如果不包括树苔,则应告知患有阳性肠道反应的患者,可能会有可能的(假)交叉反应性,以避免这种标记的香味过敏原。

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