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Assessing the validity of self‐reported history of rash caused by metal or jewellery

机译：评估金属或珠宝引起的自我报告历史的有效性

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Summary Background The use of metal‐containing bio‐devices is becoming increasingly common. Self‐reported history of dermatitis with metal exposure is not established as being predictive for metal allergy. Objectives To assess the validity of two screening questions addressing metal allergy. Methods At Massachusetts General Hospital Contact Dermatitis Clinic, 2132 consecutive patients were asked either ‘Do you get rashes when jewellery touches your skin’ (Q1; N?=?1816) or ‘Do you get rashes when metal touches your skin?’ (Q2; N?=?316) before being patch tested. Results Testing showed that 20% of subjects had positive reactions to nickel, 7.4% had positive reactions to cobalt, and 5.8% had positive reactions to chromium. Q1 was 40% sensitive (95%CI: 35–45%). The positive predictive value (PPV) was 51%, and the negative predictive value (NPV) was 82%. Q2 was 77% sensitive (95%CI: 68–84%). The PPV was 71%, and the NPV was 84%. Q2 was 37% more sensitive than Q1 ( p ??0.0001), with a higher relative risk (RR) (4.75, p ??0.001) than Q1 (RR?=?3.01, p ??0.001). Conclusions Patient‐reported metal allergy, although not perfect, is a reasonable method for metal allergy screening to help identify those needing further objective evaluation by patch testing.
机译：发明内容背景使用含金属的生物装置越来越普遍。没有建立金属暴露的自我报告的皮炎病史，因为对金属过敏的预测性。目的评估解决金属过敏的两个筛选问题的有效性。 Massachusetts综合医院的方法接触皮炎诊所，2132名连续患者被问到'当珠宝触摸你的皮肤时，你会皱纹'（Q1; n？=？1816）或'当金属触摸你的皮肤时，你会得到皮疹吗？'（Q2 ; n？=？316）在贴片之前测试。结果检测表明，20％的受试者对镍具有阳性反应，7.4％对钴具有阳性反应，5.8％对铬具有阳性反应。 Q1敏感40％（95％CI：35-45％）。阳性预测值（PPV）为51％，负预测值（NPV）为82％。 Q2敏感77％（95％CI：68-84％）。 PPV为71％，NPV为84％。 Q2比Q1（p≤≤0.0001）比Q1更高的37％，具有比Q1更高的风险（RR）（4.75，P≤X.001）（RRα= 3.01，P≤0.001 ）。结论患者报告的金属过敏，虽然不完美，是金属过敏筛查的合理方法，以帮助识别补丁检测需要进一步客观评价的方法。

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