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首页> 外文期刊>Contact dermatitis >Is a specific eyelid patch test series useful? Results of a French prospective study
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Is a specific eyelid patch test series useful? Results of a French prospective study

机译：特定的眼睑贴剂测试系列有用吗？ 法国预期研究的结果

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Background Eyelids are frequent sites of contact dermatitis. No prospective study focused on eyelid allergic contact dermatitis (EACD) has yet been published, and this topic has never been studied in French patients. Objectives To prospectively evaluate the usefulness of an eyelid series in French patients patch tested because of EACD, and to describe these patients. Methods We prospectively analysed standardized data for all patients referred to our departments between September 2014 and August 2016 for patch testing for suspected EACD as the main reason. All patients were patch tested with an eyelid series, the European baseline series (EBS), the French additional series, and their personal products. Patch testing with additional series and repeated open application tests (ROATs) or open tests were performed if necessary. A standardized assessment of the relevance was used, and the analysis of the results was focused on patients having positive test results with a current certain relevance. Results Two‐hundred and sixty‐four patients (238 women and 26 men) were included. Three‐hundred and twenty‐two tests gave positive results in 167 patients, 84 of whom had currently relevant reactions: 56 had currently relevant positive test reactions to the EBS, 16 had currently relevant positive test reactions to their personal products, 8 had currently relevant positive test reactions to the French additional series, and 4 had currently relevant positive test reactions to the eyelid series. Sixty‐seven per cent of all relevant cases were related to cosmetic products. The most frequent allergens with current relevance were methylisothiazolinone (10.2%), fragrance mix I (3%), nickel (2.7%), hydroxyperoxides of linalool (2.7%) and limonene (2.3%), and Myroxylon pereirae (2.3%). Current atopic dermatitis was found in 9.5% of patients. The duration of dermatitis was shorter (23.2 vs 34.2 months; P ?=?.035) in patients with currently relevant test reactions. The percentage of currently relevant tests remained the same when atopic patients or dermatitis localized only on the eyelids were taken into account. Conclusion In French patients, testing for EACD with the extended baseline series and personal products, also including ROATs and use tests, appears to be adequate, considering the currently relevant positive test reactions. The regular addition of an eyelid series does not seem to be necessary.
机译：背景眼睑是频繁的接触皮炎部位。没有专注于眼睑过敏性接触皮炎（EACD）的前瞻性研究尚未发表，而且本主题从未在法国患者中进行过研究。目的是在对法国患者贴片中进行前瞻性评估眼睑系列的有用性，因为EACD测试，并描述这些患者。方法对2014年9月至2016年9月至2016年8月的所有患者进行标准化数据，涉及疑似EACD作为主要原因的补丁测试。所有患者都用眼睑系列，欧洲基准系列（EBS），法国附加系列及其个人产品进行了贴片。如有必要，使用附加系列和重复打开的应用测试（Roats）或开放式测试进行补丁测试。使用了对相关性的标准化评估，并对结果的分析集中在具有当前某些相关性的患者的患者。结果二百六十四名患者（238名妇女和26名男子）被包括在内。三百二十两次测试在167名患者中得到了阳性结果，其中84名目前有关的反应：56目前对EBS的相关阳性测试反应，16次对其个人产品有相关的阳性测试反应，目前曾目前有关对法国附加系列的阳性测试反应，以及目前对眼睑系列相关的正测试反应。所有相关病例的六十七百％与化妆品有关。具有当前相关性的最常见的过敏原是甲基异噻唑啉酮（10.2％），香料混合物I（3％），镍氢（2.7％），烯丙烯酸羟基氧化氢（2.7％）和柠檬烯（2.3％）和麦小酮（2.3％）（2.3％）。 9.5％的患者中发现了目前的特征性皮炎。皮炎的持续时间短（23.2 vs 34.2个月; p？=β.035）目前相关的测试反应。当仅考虑仅考虑眼睑时，当前相关测试的百分比仍然是相同的。结论在法国患者中，考虑目前相关的阳性测试反应，患有扩展基线系列和个人产品的EACD测试，也包括ROAT和使用测试，还具有足够的阳性测试反应。似乎不需要正常添加眼睑系列。

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