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首页> 外文期刊>Acta microbiologica et immunologica Hungarica: A quarterly of the Hungarian Academy of Sciences >Antimicrobial effects of Piper guineense 'Uziza' and Phyllantus amarus 'Ebe-benizo' on Candida albicans and Streptococcus faecalis.
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Antimicrobial effects of Piper guineense 'Uziza' and Phyllantus amarus 'Ebe-benizo' on Candida albicans and Streptococcus faecalis.

机译：Piper guineense'Uziza'和Phyllantus amarus'Ebe-benizo'对白色念珠菌和粪链球菌的抗菌作用。

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摘要

Two pathogens were employed, Streptococcus faecalis and Candida albicans for the study of the antimicrobial effects of Piper guineense and Phyllantus amarus using agar-well diffusion and disc-diffusion methods. Phytochemical screening of ethanol, cold and hot water extracts detected the presence of tannins, saponins, flavonoids, terpenoids and phlobatannins. Antimicrobial effect of the plant extracts showed that the organic solvent and aqueous solvents of P. amarus were inhibitory to S. faecalis while the extracts of Phyllantus amarus were not inhibitory to Candida albicans. Agar-well determined Minimum Inhibitory Concentration (MIC) values ranged between 3.125 mg/ml and 6.25 mg/ml while the disc diffusion determined MIC values ranged between 6.25 mg/ml and 25.0 mg/ml. The agar-well determined MIC values for the ethanolic P. amarus extracts (3.12 mg/ml) were lower than the corresponding disc-diffusion MIC determined values (6.25 mg/ml-25.00 mg/ml). Bacteriocidal and bacteriostatic effect varied with, solvent type of extract, concentration of the plant extract and the method of the test adopted. The active components of the plant have no antifungal effect on the tested yeast (Candida albicans). These findings are discussed in relation to plant chemicals as a means of disease control and also to the problem of microbial resistance to synthetic drugs.
机译：使用两种病原体，粪便链球菌和白色念珠菌，通过琼脂孔扩散和圆盘扩散方法研究Piper guineense和Phyllantus amarus的抗菌作用。乙醇，冷水和热水提取物的植物化学筛选检测到单宁，皂角苷，类黄酮，萜类化合物和环巴丹宁的存在。植物提取物的抑菌作用表明，a菜的有机溶剂和水性溶剂均对粪链球菌具有抑制作用，而Ph菜的提取物对白色念珠菌没有抑制作用。琼脂孔测定的最小抑菌浓度（MIC）值介于3.125 mg / ml和6.25 mg / ml之间，而椎间盘扩散测定的MIC值介于6.25 mg / ml和25.0 mg / ml之间。乙醇P菜提取物的琼脂孔测定MIC值（3.12 mg / ml）低于相应的圆盘扩散MIC测定值（6.25 mg / ml-25.00 mg / ml）。杀菌和抑菌效果随提取物的溶剂类型，植物提取物的浓度和采用的测试方法而异。植物的活性成分对测试的酵母（白色念珠菌）没有抗真菌作用。这些发现与植物化学物质作为疾病控制手段以及微生物对合成药物的耐药性问题进行了讨论。

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